| SP | Koufax, S.Koufax, Sandy $ >> | 30 | 1965 | L | 98 | 19 | 19 | 5 | 6 | 4.26 | .300 | 1.26 | 9.3 | 2.1 | 6.5 | 135.1 | 140 | 67 | 64 | 22 | 31 | 97 | 3 | 0 | 0 | 0 | 14 | 3 | 2 | 4.44 |
| SP | Leonard, D.Leonard, Dutch # >> | 22 | 1914 | L | 91 | 18 | 18 | 5 | 7 | 3.68 | .305 | 1.28 | 7.4 | 4.1 | 6.3 | 120.0 | 98 | 54 | 49 | 6 | 55 | 84 | 0 | 0 | 0 | 0 | 10 | 5 | 4 | 3.75 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 54 | 2 | 2 | 2 | 0 | 2.40 | .318 | 1.40 | 10.2 | 2.4 | 3.6 | 15.0 | 17 | 6 | 4 | 0 | 4 | 6 | 0 | 0 | 0 | 0 | 2 | 0 | 0 | 3.00 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 89 | 19 | 0 | 1 | 2 | 3.80 | .297 | 1.18 | 8.2 | 2.7 | 7.0 | 23.2 | 21 | 11 | 10 | 3 | 7 | 18 | 0 | 0 | 0 | 0 | 0 | 2 | 0 | 4.30 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 2 | 0 | 1 | 0 | 0.00 | .222 | 0.86 | 0.0 | 9.0 | 13.5 | 2.1 | 0 | 0 | 0 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| RP | Treinen, B.Treinen, Blake >> | 30 | 2018 | R | 79 | 25 | 0 | 2 | 0 | 3.91 | .276 | 1.11 | 7.6 | 2.5 | 5.8 | 25.1 | 21 | 11 | 11 | 2 | 7 | 16 | 0 | 1 | 2 | 0 | 0 | 1 | 2 | 3.72 |
| SU | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 29 | 0 | 3 | 2 | 1.91 | .187 | 0.69 | 4.6 | 1.7 | 4.9 | 37.2 | 19 | 8 | 8 | 3 | 7 | 20 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 3.54 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 18 | 18 | 4 | 10 | 7.23 | .373 | 1.76 | 12.2 | 3.7 | 8.7 | 113.1 | 153 | 97 | 91 | 25 | 47 | 109 | 0 | 0 | 0 | 0 | 3 | 2 | 4 | 5.25 |
| CL | Wagner, B.Wagner, Billy † >> | 28 | 1999 | L | 95 | 43 | 0 | 5 | 6 | 4.05 | .283 | 1.18 | 5.9 | 4.8 | 9.5 | 53.1 | 35 | 25 | 24 | 9 | 28 | 56 | 0 | 21 | 9 | 0 | 0 | 0 | 1 | 4.68 |