| SP | Fister, D.Fister, Doug >> | 27 | 2011 | R | 83 | 15 | 15 | 10 | 1 | 3.23 | .264 | 1.03 | 7.3 | 2.0 | 5.7 | 106.0 | 86 | 39 | 38 | 12 | 23 | 67 | 1 | 0 | 0 | 1 | 10 | 5 | 1 | 4.00 |
| SP | McCarthy, B.McCarthy, Brandon >> | 28 | 2011 | R | 64 | 14 | 14 | 4 | 6 | 5.01 | .325 | 1.43 | 11.8 | 1.1 | 6.4 | 88.0 | 115 | 51 | 49 | 13 | 11 | 63 | 2 | 0 | 0 | 0 | 8 | 1 | 3 | 3.90 |
| SP | Santana, E.Santana, Ervin >> | 28 | 2011 | R | 58 | 14 | 14 | 5 | 5 | 4.48 | .316 | 1.38 | 9.4 | 3.0 | 7.6 | 92.1 | 96 | 46 | 46 | 18 | 31 | 78 | 0 | 0 | 0 | 0 | 8 | 1 | 0 | 4.89 |
| CL | Papelbon, J.Papelbon, Jonathan >> | 31 | 2011 | R | 84 | 27 | 0 | 1 | 6 | 3.30 | .302 | 1.27 | 9.3 | 2.1 | 8.1 | 30.0 | 31 | 14 | 11 | 4 | 7 | 27 | 0 | 14 | 3 | 0 | 0 | 1 | 0 | 3.73 |
| SU | Robertson, D.Robertson, David >> | 26 | 2011 | R | 77 | 34 | 0 | 1 | 3 | 3.50 | .299 | 1.28 | 6.0 | 5.5 | 7.8 | 36.0 | 24 | 14 | 14 | 3 | 22 | 31 | 0 | 4 | 5 | 0 | 0 | 0 | 1 | 4.19 |
| RP | Feliz, N.Feliz, Neftali >> | 23 | 2011 | R | 59 | 34 | 0 | 0 | 0 | 0.64 | .241 | 0.95 | 3.5 | 5.1 | 7.4 | 28.1 | 11 | 3 | 2 | 0 | 16 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.07 |
| RP | Marshall, S.Marshall, Sean >> | 29 | 2011 | L | 54 | 32 | 0 | 3 | 0 | 1.59 | .239 | 0.76 | 5.8 | 1.1 | 10.6 | 17.0 | 11 | 3 | 3 | 1 | 2 | 20 | 0 | 1 | 0 | 0 | 0 | 3 | 0 | 2.29 |
| RP | Coleman, L.Coleman, Louis >> | 25 | 2011 | R | 51 | 21 | 0 | 3 | 0 | 1.52 | .211 | 0.76 | 5.5 | 1.6 | 12.1 | 23.2 | 14 | 4 | 4 | 0 | 4 | 31 | 0 | 0 | 2 | 0 | 0 | 1 | 0 | 0.96 |
| SP | Hudson, D.Hudson, Daniel >> | 24 | 2011 | R | 53 | 10 | 0 | 2 | 4 | 6.57 | .327 | 1.38 | 10.1 | 2.6 | 6.0 | 24.2 | 27 | 18 | 18 | 4 | 7 | 16 | 0 | 1 | 0 | 0 | 0 | 2 | 1 | 4.96 |