| SP | Humber, P.Humber, Philip >> | 29 | 2011 | R | 68 | 27 | 27 | 9 | 12 | 4.26 | .328 | 1.43 | 9.5 | 3.4 | 8.1 | 150.0 | 158 | 82 | 71 | 16 | 56 | 135 | 0 | 0 | 0 | 0 | 12 | 6 | 7 | 3.83 |
| RP | Marshall, S.Marshall, Sean >> | 29 | 2011 | L | 54 | 74 | 0 | 7 | 4 | 3.34 | .313 | 1.30 | 8.9 | 2.9 | 8.8 | 91.2 | 90 | 40 | 34 | 11 | 29 | 89 | 0 | 3 | 3 | 0 | 0 | 6 | 0 | 3.77 |
| RP | Litsch, J.Litsch, Jesse >> | 26 | 2011 | R | 11 | 74 | 0 | 7 | 5 | 5.05 | .329 | 1.43 | 9.2 | 3.7 | 7.0 | 128.1 | 131 | 73 | 72 | 14 | 52 | 100 | 0 | 1 | 5 | 0 | 0 | 6 | 5 | 4.22 |
| RP | Papelbon, J.Papelbon, Jonathan # >> | 31 | 2011 | R | 84 | 57 | 0 | 3 | 3 | 4.91 | .327 | 1.45 | 10.8 | 2.3 | 8.9 | 66.0 | 79 | 37 | 36 | 9 | 17 | 65 | 0 | 1 | 2 | 0 | 0 | 0 | 1 | 3.58 |
| CL | Jansen, K.Jansen, Kenley >> | 23 | 2011 | R | 92 | 70 | 0 | 2 | 7 | 2.09 | .252 | 0.96 | 5.6 | 3.0 | 9.9 | 77.1 | 48 | 19 | 18 | 7 | 26 | 85 | 0 | 27 | 2 | 0 | 0 | 4 | 0 | 3.14 |
| RP | Feliz, N.Feliz, Neftali >> | 23 | 2011 | R | 59 | 50 | 0 | 1 | 1 | 3.98 | .322 | 1.38 | 6.9 | 5.5 | 6.8 | 61.0 | 47 | 31 | 27 | 7 | 37 | 46 | 0 | 2 | 0 | 0 | 0 | 3 | 3 | 4.95 |
| SP | Arroyo, B.Arroyo, Bronson >> | 34 | 2011 | R | 5 | 23 | 16 | 3 | 3 | 8.44 | .386 | 1.86 | 13.3 | 3.6 | 7.8 | 75.2 | 111 | 73 | 71 | 15 | 30 | 65 | 0 | 1 | 0 | 0 | 3 | 2 | 0 | 5.15 |