| SP | Tiant, L.Tiant, Luis # >> | 28 | 1968 | R | 97 | 29 | 29 | 8 | 16 | 3.70 | .287 | 1.19 | 7.5 | 3.3 | 7.9 | 204.1 | 170 | 89 | 84 | 27 | 74 | 178 | 4 | 0 | 0 | 2 | 17 | 3 | 3 | 4.11 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 27 | 27 | 10 | 13 | 4.78 | .309 | 1.33 | 9.2 | 2.8 | 5.3 | 199.2 | 204 | 115 | 106 | 24 | 61 | 118 | 9 | 0 | 0 | 1 | 12 | 3 | 4 | 4.35 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 28 | 28 | 11 | 15 | 4.75 | .322 | 1.41 | 9.7 | 3.0 | 5.0 | 191.1 | 206 | 114 | 101 | 21 | 63 | 106 | 10 | 0 | 0 | 4 | 10 | 4 | 7 | 4.37 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 60 | 27 | 27 | 6 | 11 | 5.88 | .372 | 1.74 | 10.6 | 5.1 | 7.7 | 142.1 | 167 | 97 | 93 | 19 | 80 | 122 | 0 | 0 | 0 | 0 | 9 | 6 | 1 | 4.84 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 70 | 0 | 4 | 6 | 3.54 | .270 | 1.09 | 7.4 | 2.5 | 8.6 | 101.2 | 83 | 41 | 40 | 11 | 28 | 97 | 0 | 4 | 5 | 0 | 0 | 2 | 0 | 3.39 |
| RP | Bautista, F.Bautista, Félix # >> | 28 | 2023 | R | 75 | 57 | 0 | 2 | 6 | 6.16 | .372 | 1.73 | 10.2 | 5.5 | 9.4 | 61.1 | 69 | 43 | 42 | 13 | 37 | 64 | 0 | 5 | 2 | 0 | 0 | 3 | 7 | 5.64 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 45 | 0 | 2 | 1 | 3.10 | .307 | 1.33 | 7.1 | 4.9 | 8.7 | 61.0 | 48 | 22 | 21 | 7 | 33 | 59 | 0 | 2 | 1 | 0 | 0 | 0 | 3 | 4.18 |
| RP | Fingers, R.Fingers, Rollie >> | 35 | 1981 | R | 54 | 49 | 0 | 3 | 3 | 3.16 | .270 | 1.11 | 7.8 | 2.3 | 5.3 | 68.1 | 59 | 24 | 24 | 7 | 17 | 40 | 0 | 5 | 1 | 0 | 0 | 0 | 2 | 3.91 |
| RP | Williamson, S.Williamson, Scott >> | 23 | 1999 | R | 45 | 28 | 0 | 1 | 1 | 3.67 | .321 | 1.42 | 8.1 | 4.8 | 9.2 | 41.2 | 37 | 17 | 17 | 6 | 22 | 42 | 0 | 2 | 0 | 0 | 0 | 0 | 3 | 4.46 |
| SP | Saberhagen, B.Saberhagen, Bret >> | 25 | 1989 | R | 51 | 11 | 1 | 0 | 3 | 6.19 | .314 | 1.38 | 10.1 | 2.3 | 1.7 | 16.0 | 18 | 11 | 11 | 2 | 4 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |