| SP | Leonard, D.Leonard, Dutch $ >> | 22 | 1914 | L | 91 | 28 | 28 | 17 | 4 | 2.90 | .268 | 1.07 | 7.0 | 2.7 | 4.9 | 198.2 | 153 | 64 | 64 | 18 | 59 | 107 | 3 | 0 | 0 | 0 | 19 | 6 | 1 | 4.09 |
| SP | Mathewson, C.Mathewson, Christy >> | 28 | 1908 | R | 83 | 28 | 28 | 16 | 8 | 4.36 | .311 | 1.32 | 9.7 | 2.2 | 4.9 | 198.0 | 213 | 100 | 96 | 12 | 49 | 108 | 3 | 0 | 0 | 2 | 14 | 6 | 7 | 3.53 |
| SP | Scherzer, M.Scherzer, Max # $ >> | 33 | 2017 | R | 95 | 29 | 29 | 13 | 10 | 4.29 | .284 | 1.18 | 8.2 | 2.4 | 9.0 | 189.0 | 173 | 93 | 90 | 26 | 50 | 189 | 0 | 0 | 0 | 0 | 15 | 2 | 1 | 3.61 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 27 | 27 | 11 | 8 | 4.03 | .261 | 1.05 | 7.4 | 2.0 | 5.5 | 203.0 | 168 | 96 | 91 | 30 | 45 | 125 | 6 | 0 | 0 | 2 | 13 | 2 | 2 | 4.38 |
| RP | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 80 | 0 | 4 | 2 | 1.22 | .203 | 0.75 | 4.5 | 2.3 | 9.7 | 103.2 | 52 | 16 | 14 | 4 | 26 | 111 | 0 | 16 | 3 | 0 | 0 | 1 | 0 | 2.14 |
| RP | Urbina, U.Urbina, Ugueth >> | 24 | 1998 | R | 59 | 34 | 0 | 1 | 2 | 3.41 | .290 | 1.22 | 5.6 | 5.6 | 8.2 | 34.1 | 21 | 14 | 13 | 3 | 21 | 31 | 0 | 7 | 1 | 0 | 0 | 0 | 0 | 4.18 |
| RP | Messersmith, A.Messersmith, Andy # >> | 23 | 1968 | R | 58 | 29 | 0 | 7 | 1 | 4.69 | .320 | 1.39 | 7.7 | 5.0 | 5.6 | 40.1 | 34 | 22 | 21 | 3 | 22 | 25 | 0 | 5 | 1 | 0 | 0 | 1 | 1 | 4.45 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 22 | 0 | 1 | 1 | 1.51 | .246 | 0.98 | 5.7 | 3.3 | 7.2 | 35.2 | 22 | 6 | 6 | 0 | 13 | 28 | 0 | 2 | 2 | 0 | 0 | 0 | 1 | 2.51 |