| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 23 | 23 | 13 | 4 | 2.59 | .263 | 1.04 | 6.6 | 2.8 | 8.2 | 184.1 | 135 | 57 | 53 | 18 | 57 | 167 | 9 | 0 | 0 | 2 | 16 | 5 | 1 | 3.47 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 22 | 22 | 7 | 9 | 4.83 | .294 | 1.24 | 8.0 | 3.1 | 5.8 | 136.0 | 121 | 75 | 73 | 24 | 47 | 88 | 1 | 0 | 0 | 1 | 8 | 2 | 1 | 5.08 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 21 | 21 | 12 | 6 | 2.95 | .278 | 1.14 | 8.0 | 2.3 | 4.3 | 167.2 | 148 | 57 | 55 | 10 | 43 | 80 | 7 | 0 | 0 | 1 | 13 | 3 | 2 | 3.65 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 18 | 0 | 2 | 2 | 1.96 | .250 | 0.96 | 4.3 | 4.3 | 6.7 | 23.0 | 11 | 5 | 5 | 3 | 11 | 17 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 4.78 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 7 | 0 | 1 | 2 | 4.22 | .238 | 0.94 | 7.2 | 1.8 | 5.4 | 10.2 | 8 | 5 | 5 | 3 | 2 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 6.30 |
| RP | Messersmith, A.Messersmith, Andy >> | 23 | 1968 | R | 58 | 3 | 0 | 0 | 0 | 5.40 | .167 | 0.60 | 3.6 | 1.8 | 5.4 | 5.0 | 2 | 3 | 3 | 2 | 1 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.60 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 11 | 0 | 0 | 0 | 3.07 | .228 | 0.89 | 5.1 | 3.2 | 7.7 | 14.2 | 8 | 5 | 5 | 1 | 5 | 12 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 3.29 |
| CL | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 36 | 0 | 3 | 4 | 2.58 | .223 | 0.86 | 5.9 | 1.9 | 9.5 | 38.1 | 25 | 11 | 11 | 5 | 8 | 40 | 0 | 22 | 3 | 0 | 0 | 0 | 2 | 3.24 |
| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 74 | 4 | 0 | 0 | 1 | 5.48 | .326 | 1.45 | 9.9 | 3.4 | 3.4 | 21.1 | 23 | 13 | 13 | 3 | 8 | 8 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 5.24 |