| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 23 | 23 | 8 | 10 | 2.96 | .267 | 1.08 | 7.4 | 2.3 | 10.2 | 155.0 | 128 | 55 | 51 | 11 | 39 | 175 | 1 | 0 | 0 | 0 | 15 | 2 | 0 | 2.46 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 21 | 21 | 8 | 8 | 6.23 | .334 | 1.48 | 9.8 | 3.6 | 5.3 | 138.2 | 150 | 99 | 96 | 22 | 55 | 82 | 2 | 0 | 0 | 1 | 7 | 4 | 4 | 5.17 |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 21 | 21 | 7 | 8 | 4.08 | .319 | 1.36 | 8.5 | 3.8 | 4.3 | 170.0 | 161 | 81 | 77 | 16 | 71 | 81 | 11 | 0 | 0 | 0 | 12 | 7 | 6 | 4.65 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 20 | 20 | 4 | 5 | 4.58 | .328 | 1.46 | 9.9 | 3.4 | 4.4 | 125.2 | 137 | 67 | 64 | 17 | 47 | 61 | 1 | 0 | 0 | 0 | 8 | 0 | 2 | 4.92 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 54 | 0 | 4 | 3 | 2.80 | .259 | 1.03 | 6.0 | 3.3 | 8.9 | 70.2 | 47 | 26 | 22 | 8 | 26 | 69 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 3.67 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 69 | 52 | 0 | 5 | 9 | 4.52 | .346 | 1.57 | 9.7 | 4.6 | 6.9 | 65.2 | 70 | 35 | 33 | 13 | 33 | 50 | 0 | 9 | 4 | 0 | 0 | 1 | 5 | 5.63 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 63 | 25 | 0 | 2 | 3 | 5.52 | .362 | 1.67 | 9.6 | 5.6 | 9.0 | 29.1 | 31 | 20 | 18 | 6 | 18 | 29 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 5.66 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 28 | 0 | 0 | 2 | 6.30 | .328 | 1.43 | 9.0 | 3.9 | 9.9 | 30.0 | 30 | 21 | 21 | 9 | 13 | 33 | 0 | 3 | 1 | 0 | 0 | 1 | 5 | 6.10 |
| SP | Halladay, R.Halladay, Roy >> | 28 | 2005 | R | 48 | 2 | 0 | 0 | 1 | 4.15 | .278 | 1.15 | 11.3 | 0.0 | 4.5 | 4.1 | 5 | 2 | 2 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.00 |