| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 16 | 16 | 10 | 3 | 3.06 | .241 | 0.95 | 7.1 | 1.5 | 8.9 | 109.0 | 86 | 37 | 37 | 15 | 18 | 108 | 0 | 0 | 0 | 0 | 11 | 0 | 0 | 3.30 |
| SP | Sutton, D.Sutton, Don # >> | 27 | 1972 | R | 82 | 16 | 15 | 6 | 7 | 4.97 | .311 | 1.34 | 9.5 | 2.6 | 4.5 | 92.1 | 97 | 52 | 51 | 12 | 27 | 46 | 4 | 1 | 0 | 0 | 7 | 1 | 3 | 4.61 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 78 | 15 | 15 | 5 | 6 | 5.34 | .326 | 1.45 | 9.9 | 3.1 | 6.4 | 86.0 | 95 | 52 | 51 | 12 | 30 | 61 | 1 | 0 | 0 | 0 | 6 | 0 | 3 | 4.44 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 43 | 0 | 4 | 1 | 0.83 | .165 | 0.59 | 3.7 | 1.7 | 8.7 | 54.0 | 22 | 6 | 5 | 1 | 10 | 52 | 0 | 16 | 2 | 0 | 0 | 0 | 2 | 1.87 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 44 | 0 | 2 | 2 | 3.79 | .311 | 1.32 | 6.8 | 5.2 | 8.3 | 54.2 | 41 | 28 | 23 | 5 | 31 | 50 | 0 | 3 | 1 | 0 | 0 | 2 | 0 | 4.19 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 90 | 44 | 0 | 5 | 0 | 2.63 | .281 | 1.17 | 6.8 | 3.8 | 6.2 | 68.1 | 51 | 24 | 20 | 5 | 29 | 47 | 0 | 1 | 1 | 0 | 0 | 0 | 1 | 3.85 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 84 | 35 | 0 | 2 | 0 | 2.18 | .279 | 1.14 | 5.5 | 4.8 | 9.2 | 41.1 | 25 | 10 | 10 | 1 | 22 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 2.95 |