| SP | Verlander, J.Verlander, Justin # >> | 36 | 2019 | R | 99 | 22 | 22 | 7 | 8 | 4.43 | .305 | 1.30 | 9.3 | 2.4 | 9.1 | 138.0 | 143 | 75 | 68 | 19 | 37 | 140 | 3 | 0 | 0 | 1 | 12 | 2 | 1 | 3.61 |
| SP | Johnson, R.Johnson, Randy # >> | 41 | 2004 | L | 84 | 21 | 21 | 5 | 10 | 6.47 | .348 | 1.60 | 11.4 | 3.1 | 8.0 | 111.1 | 140 | 84 | 80 | 19 | 38 | 99 | 2 | 0 | 0 | 0 | 7 | 0 | 2 | 4.47 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 23 | 21 | 4 | 11 | 6.99 | .391 | 1.90 | 12.6 | 4.5 | 6.5 | 103.0 | 144 | 85 | 80 | 22 | 52 | 74 | 0 | 0 | 0 | 0 | 7 | 2 | 2 | 5.91 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 80 | 22 | 21 | 6 | 9 | 5.51 | .329 | 1.46 | 9.6 | 3.7 | 6.6 | 112.2 | 119 | 70 | 69 | 18 | 46 | 82 | 0 | 0 | 0 | 0 | 8 | 1 | 3 | 4.88 |
| SP | McLain, D.McLain, Denny >> | 24 | 1968 | R | 79 | 25 | 21 | 10 | 5 | 5.34 | .329 | 1.44 | 10.1 | 2.9 | 6.1 | 128.0 | 143 | 84 | 76 | 21 | 41 | 87 | 4 | 2 | 0 | 1 | 9 | 4 | 2 | 4.83 |
| CL | Adams, M.Adams, Mike † >> | 31 | 2009 | R | 99 | 53 | 0 | 4 | 5 | 2.11 | .293 | 1.20 | 5.7 | 5.2 | 6.6 | 68.1 | 43 | 18 | 16 | 6 | 39 | 50 | 0 | 21 | 4 | 0 | 0 | 3 | 0 | 4.53 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 66 | 0 | 2 | 1 | 4.64 | .318 | 1.39 | 10.3 | 2.3 | 8.9 | 75.2 | 86 | 40 | 39 | 10 | 19 | 74 | 0 | 4 | 4 | 0 | 0 | 1 | 0 | 3.56 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 57 | 0 | 5 | 2 | 3.53 | .305 | 1.32 | 7.7 | 4.3 | 9.7 | 63.2 | 54 | 30 | 25 | 8 | 30 | 68 | 0 | 0 | 0 | 0 | 0 | 0 | 3 | 3.92 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 78 | 61 | 0 | 3 | 0 | 3.72 | .316 | 1.36 | 7.5 | 4.8 | 9.0 | 67.2 | 56 | 29 | 28 | 5 | 36 | 67 | 0 | 1 | 3 | 0 | 0 | 2 | 2 | 3.67 |