| SP | Carlton, S.Carlton, Steve † >> | 28 | 1972 | L | 99 | 31 | 30 | 21 | 6 | 2.74 | .260 | 1.03 | 6.6 | 2.7 | 6.5 | 256.1 | 188 | 83 | 78 | 13 | 76 | 185 | 16 | 1 | 0 | 3 | 19 | 6 | 9 | 3.18 |
| SP | Skubal, T.Skubal, Tarik >> | 25 | 2022 | L | 88 | 31 | 31 | 9 | 11 | 4.48 | .321 | 1.38 | 9.2 | 3.3 | 8.2 | 168.2 | 171 | 86 | 84 | 9 | 62 | 153 | 0 | 0 | 0 | 0 | 14 | 6 | 4 | 3.09 |
| SP | Thomas, T.Thomas, Tommy >> | 28 | 1927 | R | 77 | 29 | 29 | 14 | 8 | 4.70 | .337 | 1.52 | 10.3 | 3.4 | 4.1 | 201.0 | 229 | 111 | 105 | 13 | 76 | 91 | 6 | 0 | 0 | 1 | 12 | 2 | 0 | 4.10 |
| SP | Watson, M.Watson, Mule # >> | 25 | 1921 | R | 53 | 29 | 29 | 7 | 8 | 5.69 | .345 | 1.55 | 11.6 | 2.4 | 3.9 | 140.2 | 181 | 97 | 89 | 9 | 37 | 60 | 0 | 0 | 0 | 0 | 3 | 4 | 0 | 3.86 |
| CL | Saito, T.Saito, Takashi >> | 36 | 2006 | R | 98 | 66 | 0 | 3 | 6 | 3.81 | .318 | 1.38 | 9.8 | 2.7 | 7.2 | 78.0 | 85 | 34 | 33 | 6 | 23 | 62 | 0 | 14 | 8 | 0 | 0 | 1 | 3 | 3.33 |
| RP | Rogers, T.Rogers, Taylor >> | 32 | 2023 | L | 72 | 64 | 0 | 2 | 2 | 2.67 | .292 | 1.22 | 6.4 | 4.7 | 9.6 | 77.2 | 55 | 23 | 23 | 3 | 40 | 82 | 0 | 2 | 2 | 0 | 0 | 1 | 5 | 2.97 |
| RP | Knebel, C.Knebel, Corey >> | 25 | 2017 | R | 87 | 65 | 0 | 8 | 4 | 2.81 | .298 | 1.25 | 6.3 | 4.9 | 8.2 | 77.0 | 54 | 27 | 24 | 2 | 42 | 70 | 0 | 2 | 0 | 0 | 0 | 2 | 2 | 3.23 |
| RP | Barnes, M.Barnes, Matt >> | 31 | 2021 | R | 85 | 74 | 0 | 2 | 9 | 3.68 | .288 | 1.17 | 7.7 | 2.9 | 8.8 | 88.0 | 75 | 41 | 36 | 9 | 28 | 86 | 0 | 9 | 5 | 0 | 0 | 4 | 5 | 3.47 |
| RP | Calhoun, J.Calhoun, Jeff # >> | 27 | 1985 | L | 48 | 49 | 0 | 3 | 8 | 4.34 | .297 | 1.27 | 7.7 | 3.8 | 4.6 | 76.2 | 65 | 43 | 37 | 4 | 32 | 39 | 0 | 1 | 4 | 0 | 0 | 0 | 4 | 3.92 |