| SP | Darvish, Y.Darvish, Yu † >> | 35 | 2022 | R | 98 | 19 | 19 | 8 | 8 | 3.36 | .292 | 1.23 | 8.9 | 2.3 | 8.6 | 128.2 | 126 | 48 | 48 | 3 | 32 | 122 | 1 | 0 | 0 | 1 | 15 | 1 | 6 | 2.17 |
| SP | Capuano, C.Capuano, Chris >> | 27 | 2005 | L | 48 | 13 | 10 | 4 | 5 | 3.90 | .309 | 1.34 | 8.7 | 3.4 | 6.0 | 67.0 | 65 | 29 | 29 | 3 | 25 | 45 | 0 | 0 | 0 | 0 | 4 | 0 | 1 | 3.36 |
| SP | Wacha, M.Wacha, Michael >> | 31 | 2023 | R | 85 | 18 | 18 | 7 | 4 | 3.91 | .317 | 1.37 | 9.1 | 3.3 | 7.0 | 101.1 | 102 | 45 | 44 | 8 | 37 | 79 | 0 | 0 | 0 | 0 | 9 | 2 | 1 | 3.62 |
| SP | McLain, D.McLain, Denny >> | 22 | 1966 | R | 86 | 18 | 18 | 3 | 11 | 4.57 | .347 | 1.58 | 8.8 | 5.5 | 5.1 | 114.1 | 111 | 62 | 58 | 7 | 70 | 65 | 0 | 0 | 0 | 0 | 8 | 1 | 1 | 4.53 |
| SP | Spahn, W.Spahn, Warren # >> | 36 | 1957 | L | 74 | 18 | 18 | 5 | 10 | 5.09 | .320 | 1.40 | 9.7 | 2.9 | 3.3 | 129.0 | 139 | 77 | 73 | 10 | 41 | 48 | 2 | 0 | 0 | 0 | 5 | 2 | 1 | 4.26 |
| RP | Matusz, B.Matusz, Brian >> | 26 | 2013 | L | 82 | 40 | 0 | 4 | 3 | 1.45 | .251 | 0.99 | 5.7 | 3.3 | 5.1 | 49.2 | 31 | 9 | 8 | 3 | 18 | 28 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.82 |
| RP | Swindell, G.Swindell, Greg >> | 36 | 2001 | L | 77 | 19 | 0 | 1 | 2 | 5.16 | .320 | 1.41 | 11.9 | 1.2 | 6.5 | 22.2 | 29 | 13 | 13 | 1 | 3 | 16 | 0 | 0 | 2 | 0 | 0 | 0 | 0 | 2.55 |
| CL | Percival, T.Percival, Troy >> | 27 | 1996 | R | 99 | 27 | 0 | 0 | 2 | 3.07 | .261 | 1.06 | 5.9 | 3.7 | 8.1 | 29.1 | 19 | 11 | 10 | 2 | 12 | 26 | 0 | 17 | 5 | 0 | 0 | 0 | 0 | 3.34 |
| RP | Guerra, J.Guerra, Javy >> | 28 | 2014 | R | 63 | 34 | 0 | 1 | 2 | 5.26 | .347 | 1.59 | 11.7 | 2.9 | 7.5 | 37.2 | 48 | 22 | 22 | 3 | 12 | 31 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.35 |
| RP | Rivero, F.Rivero, Felipe >> | 24 | 2016 | L | 74 | 17 | 0 | 1 | 1 | 6.43 | .425 | 2.14 | 11.6 | 7.7 | 10.3 | 14.0 | 18 | 13 | 10 | 3 | 12 | 16 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.29 |