| SP | Gausman, K.Gausman, Kevin >> | 30 | 2021 | R | 98 | 31 | 31 | 12 | 10 | 4.48 | .315 | 1.36 | 9.5 | 2.7 | 9.2 | 182.2 | 193 | 100 | 91 | 18 | 55 | 187 | 0 | 0 | 0 | 0 | 17 | 4 | 0 | 3.20 |
| SP | Smoltz, J.Smoltz, John >> | 39 | 2006 | R | 79 | 30 | 30 | 11 | 10 | 4.65 | .328 | 1.45 | 10.5 | 2.5 | 6.0 | 184.0 | 214 | 105 | 95 | 21 | 52 | 123 | 2 | 0 | 0 | 0 | 16 | 4 | 2 | 4.06 |
| SP | Spahn, W.Spahn, Warren >> | 27 | 1948 | L | 74 | 29 | 29 | 17 | 4 | 3.92 | .330 | 1.47 | 9.1 | 4.1 | 3.6 | 195.1 | 198 | 96 | 85 | 13 | 89 | 79 | 5 | 0 | 0 | 2 | 15 | 2 | 1 | 4.46 |
| SP | Turner, J.Turner, Jim # >> | 35 | 1938 | R | 64 | 29 | 29 | 13 | 14 | 5.51 | .346 | 1.56 | 11.4 | 2.7 | 3.8 | 183.0 | 232 | 125 | 112 | 22 | 54 | 77 | 4 | 0 | 0 | 1 | 10 | 4 | 3 | 4.67 |
| SP | McBride, K.McBride, Ken † >> | 26 | 1961 | R | 54 | 28 | 28 | 14 | 6 | 4.40 | .348 | 1.58 | 9.9 | 4.4 | 5.5 | 167.2 | 184 | 94 | 82 | 19 | 81 | 102 | 1 | 0 | 0 | 0 | 14 | 4 | 3 | 4.78 |
| RP | Soria, J.Soria, Joakim >> | 25 | 2009 | R | 77 | 79 | 0 | 4 | 6 | 4.92 | .324 | 1.40 | 9.3 | 3.4 | 7.5 | 93.1 | 96 | 57 | 51 | 13 | 35 | 78 | 0 | 1 | 4 | 0 | 0 | 3 | 5 | 4.37 |
| RP | Matusz, B.Matusz, Brian >> | 26 | 2013 | L | 73 | 54 | 0 | 4 | 2 | 4.26 | .342 | 1.56 | 10.7 | 3.3 | 5.4 | 57.0 | 68 | 28 | 27 | 3 | 21 | 34 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.60 |
| RP | Santana, E.Santana, Edgar >> | 26 | 2018 | R | 70 | 49 | 0 | 4 | 2 | 3.12 | .291 | 1.23 | 8.4 | 2.8 | 5.4 | 57.2 | 53 | 27 | 20 | 5 | 18 | 34 | 0 | 2 | 2 | 0 | 0 | 0 | 2 | 3.89 |
| CL | Frieri, E.Frieri, Ernesto † >> | 26 | 2012 | R | 96 | 59 | 0 | 4 | 2 | 2.64 | .254 | 1.01 | 5.3 | 3.8 | 9.0 | 64.2 | 38 | 20 | 19 | 6 | 27 | 64 | 0 | 39 | 3 | 0 | 0 | 1 | 2 | 3.53 |
| SU | Donnelly, B.Donnelly, Brendan >> | 32 | 2003 | R | 88 | 57 | 0 | 1 | 1 | 1.93 | .272 | 1.12 | 6.2 | 4.1 | 7.4 | 60.2 | 41 | 13 | 13 | 4 | 27 | 49 | 0 | 6 | 1 | 0 | 0 | 0 | 0 | 3.58 |