| SP | Williams, S.Williams, Stan >> | 32 | 1968 | R | 97 | 29 | 29 | 7 | 12 | 4.33 | .327 | 1.44 | 8.7 | 4.2 | 4.6 | 135.0 | 131 | 66 | 65 | 8 | 63 | 69 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 4.21 |
| SP | Deshaies, J.Deshaies, Jim >> | 26 | 1986 | L | 82 | 27 | 27 | 8 | 7 | 4.26 | .336 | 1.51 | 8.9 | 4.6 | 6.8 | 152.0 | 151 | 76 | 72 | 12 | 78 | 114 | 0 | 0 | 0 | 0 | 13 | 2 | 0 | 4.11 |
| SP | McDonald, B.McDonald, Ben # >> | 27 | 1994 | R | 60 | 28 | 28 | 12 | 8 | 5.58 | .323 | 1.42 | 10.0 | 2.9 | 5.2 | 180.2 | 199 | 120 | 112 | 21 | 58 | 104 | 2 | 0 | 0 | 1 | 10 | 1 | 3 | 4.34 |
| SP | Sonnanstine, A.Sonnanstine, Andy >> | 25 | 2008 | R | 46 | 27 | 27 | 9 | 12 | 5.70 | .353 | 1.61 | 11.5 | 3.0 | 5.4 | 156.1 | 199 | 105 | 99 | 20 | 52 | 93 | 0 | 0 | 0 | 0 | 11 | 5 | 3 | 4.57 |
| RP | Svanson, M.Svanson, Matt >> | 26 | 2025 | R | 97 | 75 | 0 | 9 | 3 | 3.60 | .315 | 1.36 | 7.3 | 5.0 | 7.9 | 127.2 | 103 | 52 | 51 | 10 | 70 | 111 | 0 | 4 | 5 | 0 | 0 | 3 | 2 | 4.00 |
| RP | Soria, J.Soria, Joakim # >> | 31 | 2015 | R | 82 | 68 | 0 | 4 | 4 | 4.76 | .311 | 1.33 | 8.3 | 3.8 | 6.7 | 90.2 | 83 | 49 | 48 | 10 | 38 | 67 | 0 | 5 | 2 | 0 | 0 | 2 | 5 | 4.29 |
| RP | James, M.James, Mike † >> | 33 | 2000 | R | 65 | 73 | 0 | 8 | 5 | 2.24 | .293 | 1.25 | 6.9 | 4.3 | 6.8 | 92.1 | 71 | 25 | 23 | 9 | 44 | 69 | 0 | 8 | 1 | 0 | 0 | 0 | 0 | 4.21 |
| RP | Thurmond, M.Thurmond, Mark >> | 34 | 1990 | L | 47 | 57 | 0 | 1 | 2 | 3.67 | .295 | 1.24 | 8.4 | 2.8 | 6.0 | 61.1 | 57 | 29 | 25 | 8 | 19 | 41 | 0 | 12 | 1 | 0 | 0 | 1 | 0 | 4.34 |
| RP | Diekman, J.Diekman, Jake >> | 28 | 2015 | L | 36 | 32 | 0 | 0 | 3 | 5.61 | .353 | 1.63 | 9.3 | 5.7 | 7.6 | 33.2 | 34 | 24 | 21 | 4 | 21 | 28 | 0 | 1 | 1 | 0 | 0 | 0 | 0 | 4.79 |
| SP | Pettitte, A.Pettitte, Andy >> | 37 | 2009 | L | 41 | 1 | 1 | 0 | 0 | 7.94 | .414 | 2.12 | 10.8 | 10.8 | 5.4 | 5.2 | 6 | 5 | 5 | 1 | 6 | 3 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 8.00 |
| SP | Gonzalez, G.Gonzalez, Gio >> | 33 | 2018 | L | 36 | 14 | 0 | 1 | 2 | 7.97 | .425 | 2.21 | 14.0 | 6.3 | 7.2 | 20.1 | 31 | 21 | 18 | 2 | 14 | 16 | 0 | 0 | 2 | 0 | 0 | 0 | 1 | 4.80 |