| SP | Bassitt, C.Bassitt, Chris >> | 32 | 2021 | R | 91 | 19 | 19 | 6 | 5 | 2.57 | .286 | 1.19 | 8.0 | 2.7 | 8.0 | 122.1 | 109 | 36 | 35 | 6 | 36 | 108 | 0 | 0 | 0 | 0 | 12 | 2 | 2 | 2.80 |
| SP | Eovaldi, N.Eovaldi, Nathan >> | 28 | 2018 | R | 59 | 18 | 18 | 6 | 7 | 5.08 | .317 | 1.37 | 10.3 | 2.1 | 6.3 | 95.2 | 109 | 55 | 54 | 12 | 22 | 67 | 0 | 0 | 0 | 0 | 3 | 2 | 5 | 3.99 |
| SP | Stewart, D.Stewart, Dave >> | 33 | 1990 | R | 58 | 17 | 17 | 3 | 12 | 5.17 | .320 | 1.37 | 8.8 | 3.4 | 5.0 | 115.0 | 113 | 67 | 66 | 17 | 44 | 64 | 6 | 0 | 0 | 0 | 7 | 5 | 6 | 5.09 |
| SP | Mulder, M.Mulder, Mark # >> | 25 | 2002 | L | 57 | 17 | 17 | 3 | 10 | 5.81 | .331 | 1.45 | 11.0 | 2.0 | 5.1 | 110.0 | 135 | 71 | 71 | 22 | 24 | 62 | 0 | 0 | 0 | 0 | 5 | 4 | 4 | 5.24 |
| RP | Eckersley, D.Eckersley, Dennis † >> | 36 | 1990 | R | 99 | 48 | 0 | 5 | 1 | 2.31 | .255 | 1.00 | 8.0 | 1.0 | 8.0 | 70.0 | 62 | 22 | 18 | 9 | 8 | 62 | 0 | 2 | 1 | 0 | 0 | 2 | 0 | 3.33 |
| RP | Honeycutt, R.Honeycutt, Rick >> | 36 | 1990 | L | 75 | 44 | 0 | 2 | 3 | 3.64 | .303 | 1.25 | 8.0 | 3.3 | 5.3 | 54.1 | 48 | 22 | 22 | 4 | 20 | 32 | 0 | 5 | 4 | 0 | 0 | 3 | 0 | 4.06 |
| RP | Street, H.Street, Huston >> | 25 | 2008 | R | 64 | 36 | 0 | 3 | 0 | 1.42 | .231 | 0.88 | 5.3 | 2.7 | 7.0 | 44.1 | 26 | 10 | 7 | 1 | 13 | 34 | 0 | 3 | 1 | 0 | 0 | 1 | 0 | 2.70 |
| RP | Ziegler, B.Ziegler, Brad >> | 29 | 2008 | R | 63 | 28 | 0 | 3 | 1 | 4.66 | .329 | 1.40 | 9.9 | 2.8 | 5.2 | 38.2 | 42 | 20 | 20 | 2 | 12 | 22 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 3.71 |
| RP | Trivino, L.Trivino, Lou >> | 29 | 2021 | R | 62 | 25 | 0 | 0 | 1 | 1.50 | .169 | 0.61 | 3.8 | 1.8 | 6.5 | 36.0 | 15 | 6 | 6 | 2 | 7 | 26 | 0 | 4 | 0 | 0 | 0 | 0 | 0 | 2.86 |