| SP | Overall, O.Overall, Orval >> | 28 | 1909 | R | 88 | 31 | 31 | 12 | 14 | 5.14 | .329 | 1.43 | 8.7 | 4.2 | 6.6 | 231.1 | 223 | 147 | 132 | 32 | 107 | 169 | 8 | 0 | 0 | 0 | 14 | 10 | 7 | 4.86 |
| SP | Brown, M.Brown, Mordecai # >> | 33 | 1909 | R | 92 | 30 | 30 | 11 | 14 | 4.80 | .306 | 1.30 | 9.1 | 2.7 | 5.7 | 226.2 | 228 | 130 | 121 | 28 | 67 | 144 | 10 | 0 | 0 | 2 | 14 | 5 | 4 | 4.29 |
| SP | Pfiester, J.Pfiester, Jack >> | 31 | 1909 | L | 40 | 24 | 22 | 6 | 11 | 5.62 | .341 | 1.54 | 10.5 | 3.4 | 5.1 | 158.2 | 185 | 120 | 99 | 28 | 59 | 89 | 5 | 0 | 0 | 1 | 9 | 2 | 1 | 5.34 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 90 | 29 | 29 | 9 | 11 | 3.67 | .304 | 1.29 | 9.0 | 2.7 | 6.0 | 193.2 | 192 | 100 | 79 | 27 | 57 | 128 | 0 | 0 | 0 | 0 | 17 | 5 | 5 | 4.46 |
| SP | Arrieta, J.Arrieta, Jake † >> | 30 | 2016 | R | 84 | 28 | 28 | 12 | 10 | 3.64 | .316 | 1.36 | 7.4 | 4.9 | 7.4 | 202.2 | 167 | 91 | 82 | 18 | 109 | 165 | 1 | 0 | 0 | 1 | 19 | 5 | 6 | 4.22 |
| SU | Chapman, A.Chapman, Aroldis >> | 28 | 2016 | L | 97 | 49 | 0 | 2 | 2 | 1.38 | .234 | 0.90 | 4.7 | 3.5 | 10.4 | 52.1 | 27 | 8 | 8 | 1 | 20 | 60 | 0 | 8 | 3 | 0 | 0 | 1 | 3 | 2.15 |
| CL | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 100 | 39 | 0 | 5 | 5 | 5.59 | .373 | 1.76 | 8.8 | 7.3 | 11.4 | 38.2 | 37 | 27 | 24 | 5 | 31 | 48 | 0 | 15 | 9 | 0 | 0 | 1 | 4 | 4.71 |
| RP | Hagerman, R.Hagerman, Rip >> | 21 | 1909 | R | 50 | 52 | 0 | 3 | 2 | 3.88 | .331 | 1.44 | 8.5 | 4.6 | 5.3 | 53.1 | 50 | 29 | 23 | 5 | 27 | 31 | 0 | 2 | 1 | 0 | 0 | 2 | 1 | 4.70 |
| RP | Rondon, H.Rondon, Hector >> | 28 | 2016 | R | 78 | 41 | 0 | 1 | 3 | 2.70 | .264 | 1.05 | 7.2 | 2.3 | 8.8 | 40.0 | 32 | 12 | 12 | 5 | 10 | 39 | 0 | 6 | 0 | 0 | 0 | 1 | 0 | 3.50 |
| SP | Cicotte, E.Cicotte, Eddie >> | 36 | 1920 | R | 20 | 6 | 0 | 1 | 1 | 2.89 | .282 | 1.18 | 7.0 | 4.0 | 3.0 | 9.1 | 7 | 3 | 3 | 0 | 4 | 3 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.67 |
| RP | Radinsky, S.Radinsky, Scott >> | 29 | 1997 | L | 41 | 50 | 0 | 2 | 2 | 2.54 | .259 | 1.03 | 6.2 | 3.0 | 6.0 | 39.0 | 27 | 12 | 11 | 5 | 13 | 26 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.41 |