| SP | Lincecum, T.Lincecum, Tim >> | 25 | 2009 | R | 98 | 20 | 20 | 9 | 9 | 4.51 | .322 | 1.37 | 8.6 | 3.9 | 8.2 | 123.2 | 117 | 64 | 62 | 7 | 53 | 112 | 1 | 0 | 0 | 0 | 10 | 6 | 3 | 3.36 |
| SP | Leonard, D.Leonard, Dutch # >> | 24 | 1916 | L | 81 | 19 | 19 | 6 | 10 | 5.42 | .348 | 1.60 | 11.5 | 2.9 | 5.3 | 106.1 | 136 | 68 | 64 | 12 | 34 | 63 | 0 | 0 | 0 | 0 | 6 | 0 | 2 | 4.25 |
| SP | McGinnity, J.McGinnity, Joe # >> | 35 | 1906 | R | 74 | 19 | 19 | 8 | 8 | 3.71 | .297 | 1.25 | 8.9 | 2.4 | 4.3 | 131.0 | 129 | 54 | 54 | 7 | 35 | 62 | 4 | 0 | 0 | 0 | 11 | 2 | 0 | 3.60 |
| RP | Jansen, K.Jansen, Kenley >> | 31 | 2019 | R | 89 | 48 | 0 | 1 | 1 | 2.51 | .293 | 1.20 | 8.3 | 2.5 | 9.0 | 61.0 | 56 | 22 | 17 | 3 | 17 | 61 | 0 | 1 | 1 | 0 | 0 | 3 | 1 | 2.62 |
| CL | Reardon, J.Reardon, Jeff † >> | 34 | 1989 | R | 63 | 39 | 0 | 1 | 3 | 2.11 | .269 | 1.08 | 8.4 | 1.5 | 6.6 | 42.2 | 39 | 12 | 10 | 3 | 7 | 31 | 0 | 24 | 0 | 0 | 0 | 1 | 0 | 3.02 |
| SU | Van Poppel, T.Van Poppel, Todd >> | 30 | 2001 | R | 56 | 46 | 0 | 0 | 3 | 2.41 | .252 | 1.01 | 6.4 | 2.8 | 8.0 | 52.1 | 37 | 16 | 14 | 3 | 16 | 46 | 0 | 4 | 3 | 0 | 0 | 0 | 0 | 2.90 |
| RP | Gossage, R.Gossage, Rich >> | 38 | 1989 | R | 54 | 46 | 0 | 1 | 0 | 3.25 | .322 | 1.39 | 7.9 | 4.7 | 5.1 | 55.1 | 48 | 22 | 20 | 2 | 29 | 31 | 0 | 3 | 0 | 0 | 0 | 2 | 0 | 4.04 |
| SP | Butcher, M.Butcher, Max >> | 34 | 1944 | R | 29 | 3 | 0 | 0 | 0 | 3.00 | .308 | 1.33 | 9.0 | 3.0 | 3.0 | 3.0 | 3 | 1 | 1 | 1 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 7.67 |
| RP | Tekulve, K.Tekulve, Kent >> | 32 | 1979 | R | 66 | 26 | 0 | 0 | 1 | 1.56 | .257 | 1.04 | 6.4 | 3.2 | 7.1 | 34.2 | 24 | 8 | 6 | 0 | 12 | 27 | 0 | 1 | 0 | 0 | 0 | 0 | 2 | 2.47 |
| RP | Moylan, P.Moylan, Peter >> | 32 | 2010 | R | 32 | 8 | 0 | 0 | 1 | 5.00 | .400 | 2.00 | 12.0 | 6.0 | 6.0 | 9.0 | 12 | 5 | 5 | 1 | 6 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.11 |