| SP | Martinez, P.Martinez, Pedro $ >> | 29 | 2000 | R | 100 | 30 | 30 | 13 | 13 | 3.41 | .290 | 1.20 | 7.8 | 3.0 | 9.2 | 219.1 | 191 | 88 | 83 | 27 | 72 | 225 | 4 | 0 | 0 | 1 | 20 | 6 | 4 | 3.62 |
| SP | Peavy, J.Peavy, Jake # >> | 26 | 2007 | R | 89 | 29 | 29 | 8 | 12 | 5.18 | .350 | 1.57 | 9.9 | 4.2 | 8.9 | 173.2 | 191 | 109 | 100 | 19 | 81 | 171 | 0 | 0 | 0 | 0 | 10 | 8 | 3 | 3.99 |
| SP | Pettitte, A.Pettitte, Andy >> | 33 | 2005 | L | 78 | 29 | 29 | 9 | 13 | 5.74 | .329 | 1.45 | 10.4 | 2.7 | 6.5 | 172.1 | 198 | 114 | 110 | 33 | 52 | 124 | 0 | 0 | 0 | 0 | 12 | 3 | 4 | 5.01 |
| SP | Sabathia, C.Sabathia, CC >> | 28 | 2008 | L | 60 | 28 | 28 | 11 | 9 | 5.51 | .347 | 1.58 | 11.1 | 3.1 | 7.1 | 181.1 | 224 | 127 | 111 | 29 | 62 | 142 | 0 | 0 | 0 | 0 | 10 | 3 | 3 | 4.59 |
| SP | Garcia, F.Garcia, Freddy # >> | 26 | 2001 | R | 61 | 27 | 27 | 11 | 11 | 4.87 | .335 | 1.46 | 9.9 | 3.3 | 7.0 | 166.1 | 182 | 97 | 90 | 25 | 61 | 130 | 2 | 0 | 0 | 1 | 15 | 8 | 5 | 4.64 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 85 | 83 | 0 | 1 | 4 | 3.31 | .295 | 1.21 | 8.1 | 2.8 | 8.4 | 73.1 | 66 | 33 | 27 | 6 | 23 | 68 | 0 | 1 | 2 | 0 | 0 | 3 | 5 | 3.27 |
| RP | Foulke, K.Foulke, Keith >> | 31 | 2003 | R | 78 | 59 | 0 | 2 | 5 | 4.39 | .320 | 1.39 | 10.1 | 2.5 | 9.0 | 55.1 | 62 | 32 | 27 | 11 | 15 | 55 | 0 | 0 | 5 | 0 | 0 | 1 | 0 | 4.47 |
| RP | Gonzalez, M.Gonzalez, Mike >> | 26 | 2004 | L | 74 | 81 | 0 | 6 | 1 | 3.23 | .254 | 0.99 | 6.8 | 2.2 | 7.8 | 69.2 | 52 | 32 | 25 | 6 | 17 | 60 | 0 | 3 | 2 | 0 | 0 | 2 | 4 | 3.22 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 29 | 2001 | R | 76 | 41 | 0 | 4 | 1 | 4.15 | .274 | 1.11 | 8.2 | 1.9 | 9.0 | 47.2 | 43 | 23 | 22 | 10 | 10 | 47 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.47 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 72 | 33 | 0 | 1 | 1 | 4.14 | .326 | 1.45 | 9.0 | 4.2 | 9.9 | 41.1 | 41 | 22 | 19 | 5 | 19 | 45 | 0 | 0 | 0 | 0 | 0 | 0 | 2 | 3.78 |
| CL | Gagne, E.Gagne, Eric † $$ >> | 27 | 2003 | R | 100 | 61 | 0 | 2 | 5 | 2.43 | .289 | 1.20 | 7.2 | 3.8 | 10.3 | 55.2 | 44 | 19 | 15 | 5 | 23 | 63 | 0 | 41 | 4 | 0 | 0 | 1 | 3 | 3.20 |