| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 36 | 36 | 12 | 13 | 4.09 | .287 | 1.19 | 7.8 | 3.0 | 9.4 | 211.1 | 182 | 99 | 96 | 21 | 70 | 221 | 3 | 0 | 0 | 2 | 18 | 3 | 4 | 3.24 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 35 | 35 | 12 | 12 | 4.99 | .332 | 1.46 | 10.2 | 3.0 | 4.6 | 211.0 | 238 | 125 | 117 | 33 | 71 | 108 | 2 | 0 | 0 | 0 | 15 | 5 | 1 | 5.09 |
| SP | Hendrix, C.Hendrix, Claude # >> | 25 | 1914 | R | 69 | 34 | 34 | 5 | 19 | 6.96 | .365 | 1.70 | 12.1 | 3.3 | 4.5 | 178.1 | 239 | 150 | 138 | 27 | 65 | 89 | 2 | 0 | 0 | 1 | 8 | 3 | 9 | 5.12 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 67 | 33 | 33 | 14 | 9 | 4.17 | .323 | 1.42 | 9.6 | 3.1 | 5.5 | 209.1 | 224 | 104 | 97 | 25 | 73 | 127 | 4 | 0 | 0 | 3 | 18 | 3 | 6 | 4.43 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 67 | 31 | 31 | 13 | 9 | 4.56 | .326 | 1.43 | 8.7 | 4.3 | 5.2 | 185.2 | 178 | 103 | 94 | 22 | 88 | 106 | 3 | 0 | 0 | 0 | 16 | 4 | 3 | 4.89 |
| RP | Doolittle, S.Doolittle, Sean † >> | 31 | 2018 | L | 99 | 100 | 0 | 12 | 3 | 3.77 | .295 | 1.25 | 9.2 | 2.1 | 9.6 | 102.2 | 104 | 46 | 43 | 14 | 24 | 109 | 0 | 4 | 5 | 0 | 0 | 1 | 6 | 3.38 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 95 | 111 | 0 | 7 | 1 | 3.03 | .260 | 1.02 | 6.6 | 2.6 | 7.7 | 116.0 | 85 | 41 | 39 | 15 | 33 | 99 | 0 | 5 | 2 | 0 | 0 | 4 | 0 | 3.93 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 103 | 0 | 3 | 2 | 3.31 | .306 | 1.25 | 6.0 | 5.3 | 9.6 | 73.1 | 49 | 29 | 27 | 4 | 43 | 78 | 0 | 10 | 2 | 0 | 0 | 5 | 1 | 3.55 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 87 | 0 | 2 | 2 | 3.82 | .326 | 1.42 | 8.6 | 4.3 | 8.4 | 61.1 | 58 | 28 | 26 | 3 | 29 | 57 | 0 | 6 | 2 | 0 | 0 | 2 | 3 | 3.30 |
| SP | Drysdale, D.Drysdale, Don >> | 28 | 1964 | R | 59 | 33 | 0 | 3 | 5 | 5.73 | .370 | 1.76 | 12.3 | 3.6 | 5.1 | 55.0 | 75 | 38 | 35 | 9 | 22 | 31 | 0 | 3 | 2 | 0 | 0 | 0 | 3 | 5.20 |