| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 34 | 34 | 14 | 14 | 3.25 | .286 | 1.18 | 7.9 | 2.8 | 8.6 | 229.2 | 200 | 108 | 83 | 21 | 72 | 218 | 4 | 0 | 0 | 1 | 23 | 4 | 3 | 3.28 |
| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 8 | 18 | 5.19 | .344 | 1.54 | 9.3 | 4.6 | 7.7 | 194.1 | 200 | 125 | 112 | 22 | 100 | 167 | 2 | 0 | 0 | 2 | 14 | 6 | 8 | 4.39 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 32 | 32 | 3 | 17 | 6.47 | .346 | 1.57 | 10.6 | 3.6 | 4.5 | 175.1 | 206 | 139 | 126 | 35 | 70 | 88 | 2 | 0 | 0 | 0 | 8 | 2 | 3 | 5.83 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 103 | 0 | 5 | 2 | 3.96 | .331 | 1.46 | 9.3 | 3.8 | 8.0 | 109.0 | 113 | 60 | 48 | 8 | 46 | 97 | 0 | 2 | 2 | 0 | 0 | 3 | 3 | 3.52 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 88 | 0 | 7 | 4 | 3.51 | .290 | 1.21 | 9.3 | 1.6 | 7.8 | 107.2 | 111 | 50 | 42 | 10 | 19 | 93 | 0 | 6 | 1 | 0 | 0 | 2 | 0 | 3.07 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 64 | 0 | 4 | 6 | 5.40 | .361 | 1.67 | 10.6 | 4.6 | 4.8 | 86.2 | 101 | 69 | 52 | 14 | 44 | 46 | 0 | 5 | 6 | 0 | 0 | 2 | 9 | 5.65 |
| RP | Bailey, A.Bailey, Andrew >> | 25 | 2009 | R | 67 | 49 | 0 | 1 | 1 | 5.66 | .347 | 1.57 | 9.4 | 5.0 | 8.0 | 47.2 | 49 | 35 | 30 | 6 | 26 | 42 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 4.60 |