| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 34 | 34 | 10 | 14 | 5.24 | .327 | 1.44 | 9.8 | 3.2 | 8.0 | 220.0 | 239 | 129 | 128 | 29 | 77 | 195 | 2 | 0 | 0 | 0 | 13 | 5 | 9 | 4.06 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 33 | 33 | 8 | 15 | 4.89 | .320 | 1.40 | 10.6 | 2.0 | 5.7 | 209.2 | 246 | 118 | 114 | 28 | 47 | 132 | 4 | 0 | 0 | 0 | 14 | 3 | 4 | 4.20 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 32 | 32 | 10 | 14 | 5.36 | .337 | 1.50 | 10.8 | 2.6 | 5.4 | 210.0 | 253 | 136 | 125 | 28 | 61 | 125 | 4 | 0 | 0 | 2 | 10 | 6 | 2 | 4.50 |
| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 84 | 32 | 32 | 11 | 10 | 4.88 | .341 | 1.53 | 11.1 | 2.7 | 7.7 | 204.2 | 252 | 120 | 111 | 29 | 61 | 175 | 1 | 0 | 0 | 0 | 14 | 5 | 3 | 4.10 |
| CL | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 67 | 0 | 3 | 7 | 4.91 | .346 | 1.54 | 10.3 | 3.6 | 8.4 | 62.1 | 71 | 35 | 34 | 9 | 25 | 58 | 0 | 27 | 6 | 0 | 0 | 3 | 0 | 4.37 |
| SU | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 82 | 0 | 4 | 3 | 3.99 | .312 | 1.34 | 7.0 | 5.1 | 7.9 | 90.1 | 70 | 44 | 40 | 8 | 51 | 79 | 0 | 4 | 7 | 0 | 0 | 2 | 0 | 4.17 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 86 | 0 | 5 | 8 | 5.01 | .338 | 1.51 | 10.2 | 3.5 | 8.2 | 100.2 | 113 | 57 | 56 | 22 | 39 | 91 | 0 | 0 | 1 | 0 | 0 | 2 | 2 | 5.27 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 70 | 0 | 3 | 3 | 5.47 | .351 | 1.60 | 10.0 | 4.6 | 9.1 | 75.2 | 83 | 53 | 46 | 8 | 38 | 76 | 0 | 2 | 1 | 0 | 0 | 2 | 4 | 3.96 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 55 | 0 | 5 | 1 | 5.14 | .314 | 1.36 | 7.8 | 4.4 | 8.6 | 70.0 | 61 | 40 | 40 | 7 | 34 | 67 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 3.89 |