| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 22 | 22 | 5 | 10 | 4.65 | .319 | 1.39 | 8.9 | 3.7 | 8.9 | 127.2 | 126 | 71 | 66 | 13 | 52 | 126 | 1 | 0 | 0 | 0 | 12 | 1 | 4 | 3.60 |
| SP | Mathewson, C.Mathewson, Christy $ >> | 28 | 1908 | R | 83 | 23 | 23 | 7 | 8 | 4.76 | .306 | 1.30 | 9.4 | 2.3 | 5.4 | 147.1 | 154 | 78 | 78 | 16 | 38 | 89 | 3 | 0 | 0 | 0 | 11 | 3 | 4 | 4.04 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 22 | 22 | 8 | 7 | 4.15 | .308 | 1.32 | 9.3 | 2.6 | 6.0 | 132.1 | 137 | 65 | 61 | 11 | 38 | 88 | 0 | 0 | 0 | 0 | 10 | 2 | 0 | 3.66 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 68 | 22 | 22 | 10 | 7 | 4.98 | .322 | 1.38 | 9.2 | 3.3 | 6.6 | 137.1 | 140 | 86 | 76 | 20 | 50 | 101 | 1 | 0 | 0 | 1 | 11 | 6 | 5 | 4.65 |
| CL | Gagne, E.Gagne, Eric † >> | 27 | 2003 | R | 98 | 48 | 0 | 7 | 5 | 2.49 | .283 | 1.14 | 7.4 | 3.1 | 8.5 | 50.2 | 41 | 16 | 14 | 4 | 17 | 47 | 0 | 28 | 2 | 0 | 0 | 2 | 0 | 3.30 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 85 | 53 | 0 | 1 | 3 | 3.56 | .317 | 1.39 | 10.6 | 2.0 | 9.1 | 68.1 | 80 | 30 | 27 | 6 | 15 | 69 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 2.78 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 77 | 43 | 0 | 2 | 2 | 4.24 | .307 | 1.29 | 8.6 | 3.1 | 8.2 | 46.2 | 44 | 27 | 22 | 5 | 16 | 42 | 0 | 0 | 2 | 0 | 0 | 2 | 4 | 3.76 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 73 | 37 | 0 | 2 | 4 | 4.82 | .321 | 1.39 | 9.0 | 3.6 | 8.8 | 37.1 | 37 | 20 | 20 | 11 | 15 | 36 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 6.22 |