| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 15 | 15 | 3 | 8 | 4.52 | .323 | 1.41 | 9.4 | 3.4 | 8.1 | 95.2 | 99 | 58 | 48 | 11 | 36 | 86 | 1 | 0 | 0 | 0 | 7 | 2 | 3 | 3.89 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 90 | 15 | 15 | 4 | 5 | 5.09 | .321 | 1.42 | 10.1 | 2.7 | 9.2 | 88.1 | 99 | 56 | 50 | 18 | 26 | 90 | 1 | 0 | 0 | 1 | 6 | 0 | 2 | 4.50 |
| SP | Alexander, P.Alexander, Pete >> | 28 | 1915 | R | 88 | 15 | 15 | 4 | 7 | 6.67 | .319 | 1.39 | 9.8 | 2.8 | 5.0 | 79.2 | 86 | 61 | 59 | 16 | 25 | 44 | 3 | 0 | 0 | 0 | 6 | 1 | 2 | 5.51 |
| CL | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 43 | 0 | 3 | 3 | 7.45 | .358 | 1.66 | 12.0 | 3.0 | 10.5 | 48.1 | 64 | 43 | 40 | 12 | 16 | 56 | 0 | 13 | 5 | 0 | 0 | 1 | 0 | 4.98 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 47 | 0 | 0 | 2 | 7.07 | .371 | 1.77 | 10.5 | 5.7 | 9.7 | 49.2 | 57 | 41 | 39 | 5 | 31 | 53 | 0 | 2 | 3 | 0 | 0 | 0 | 5 | 4.06 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 34 | 0 | 6 | 0 | 4.03 | .380 | 1.79 | 9.2 | 6.9 | 10.2 | 38.0 | 39 | 19 | 17 | 4 | 29 | 43 | 0 | 0 | 0 | 0 | 0 | 2 | 4 | 4.55 |