| SP | Skubal, T.Skubal, Tarik >> | 28 | 2025 | L | 100 | 16 | 16 | 8 | 2 | 3.74 | .277 | 1.10 | 7.6 | 2.4 | 10.3 | 106.0 | 89 | 44 | 44 | 13 | 28 | 121 | 1 | 0 | 0 | 1 | 8 | 5 | 3 | 3.25 |
| SP | Nelson, R.Nelson, Ryne >> | 27 | 2025 | R | 79 | 16 | 16 | 6 | 9 | 6.23 | .332 | 1.45 | 10.4 | 2.8 | 7.5 | 73.2 | 84 | 57 | 51 | 15 | 23 | 61 | 0 | 0 | 0 | 0 | 2 | 3 | 1 | 5.07 |
| SP | Kirby, G.Kirby, George >> | 27 | 2025 | R | 61 | 15 | 15 | 5 | 5 | 5.33 | .323 | 1.39 | 9.5 | 3.2 | 10.5 | 77.2 | 81 | 46 | 46 | 12 | 27 | 90 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 3.86 |
| RP | Keller, B.Keller, Brad >> | 29 | 2025 | R | 87 | 40 | 0 | 1 | 0 | 2.39 | .269 | 1.10 | 6.9 | 3.1 | 10.0 | 52.2 | 40 | 14 | 14 | 6 | 18 | 58 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 3.31 |
| RP | Kittredge, A.Kittredge, Andrew >> | 35 | 2025 | R | 82 | 37 | 0 | 2 | 1 | 2.82 | .285 | 1.20 | 7.9 | 2.8 | 9.7 | 51.0 | 45 | 16 | 16 | 5 | 16 | 55 | 0 | 3 | 0 | 0 | 0 | 0 | 2 | 3.06 |
| RP | Rogers, T.Rogers, Tyler >> | 34 | 2025 | R | 66 | 30 | 0 | 2 | 0 | 4.11 | .276 | 1.06 | 8.7 | 0.8 | 9.5 | 35.0 | 34 | 16 | 16 | 4 | 3 | 37 | 0 | 5 | 2 | 0 | 0 | 3 | 0 | 2.89 |
| RP | Morejon, A.Morejon, Adrian >> | 26 | 2025 | L | 87 | 30 | 0 | 2 | 0 | 5.34 | .304 | 1.31 | 9.3 | 2.5 | 7.3 | 32.0 | 33 | 19 | 19 | 3 | 9 | 26 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 3.44 |