| SP | Hooton, B.Hooton, Burt † # >> | 27 | 1977 | R | 92 | 33 | 33 | 15 | 13 | 3.26 | .290 | 1.21 | 8.2 | 2.6 | 5.7 | 245.1 | 224 | 98 | 89 | 25 | 72 | 154 | 5 | 0 | 0 | 2 | 21 | 5 | 5 | 4.01 |
| SP | Castillo, B.Castillo, Bobby >> | 27 | 1982 | R | 70 | 32 | 32 | 8 | 13 | 5.36 | .355 | 1.64 | 10.6 | 4.2 | 4.2 | 166.1 | 195 | 112 | 99 | 10 | 77 | 78 | 0 | 0 | 0 | 0 | 9 | 3 | 7 | 4.29 |
| SP | Navarro, J.Navarro, Jaime >> | 28 | 1995 | R | 67 | 31 | 31 | 10 | 9 | 6.64 | .346 | 1.57 | 9.9 | 4.2 | 5.8 | 188.1 | 207 | 144 | 139 | 20 | 88 | 122 | 1 | 0 | 0 | 0 | 8 | 4 | 7 | 4.55 |
| SP | Fernandez, A.Fernandez, Alex >> | 23 | 1992 | R | 45 | 30 | 30 | 4 | 17 | 6.62 | .366 | 1.70 | 11.4 | 3.9 | 5.4 | 178.0 | 225 | 141 | 131 | 23 | 77 | 106 | 0 | 0 | 0 | 0 | 7 | 6 | 5 | 4.89 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 28 | 2008 | R | 92 | 93 | 0 | 5 | 5 | 4.21 | .310 | 1.34 | 10.1 | 1.9 | 9.7 | 107.0 | 120 | 51 | 50 | 7 | 23 | 115 | 0 | 10 | 2 | 0 | 0 | 1 | 2 | 2.37 |
| RP | Dotel, O.Dotel, Octavio # >> | 37 | 2010 | R | 73 | 74 | 0 | 4 | 3 | 4.76 | .331 | 1.44 | 7.5 | 5.4 | 8.3 | 85.0 | 71 | 46 | 45 | 6 | 51 | 78 | 0 | 5 | 6 | 0 | 0 | 4 | 7 | 4.02 |
| RP | Lopez, J.Lopez, Javier >> | 31 | 2008 | L | 46 | 99 | 0 | 6 | 2 | 4.72 | .334 | 1.49 | 8.0 | 5.6 | 5.6 | 89.2 | 79 | 51 | 47 | 7 | 55 | 55 | 0 | 5 | 3 | 0 | 0 | 1 | 1 | 4.67 |
| RP | Paniagua, J.Paniagua, Jose >> | 28 | 2001 | R | 32 | 73 | 0 | 1 | 9 | 6.38 | .389 | 1.87 | 9.7 | 7.2 | 6.2 | 73.1 | 79 | 61 | 52 | 7 | 58 | 50 | 0 | 5 | 6 | 0 | 0 | 3 | 2 | 5.38 |
| SP | Moreno, J.Moreno, Julio >> | 31 | 1952 | R | 32 | 2 | 0 | 0 | 0 | 0.00 | .250 | 1.00 | 4.5 | 4.5 | 0.0 | 2.0 | 1 | 0 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.50 |
| SP | Freeland, K.Freeland, Kyle >> | 32 | 2025 | L | 20 | 6 | 0 | 0 | 1 | 11.81 | .484 | 2.81 | 18.0 | 9.0 | 0.0 | 5.1 | 10 | 7 | 7 | 0 | 5 | 0 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 6.00 |