| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 32 | 32 | 9 | 15 | 3.77 | .290 | 1.21 | 8.0 | 2.9 | 8.7 | 207.2 | 185 | 90 | 87 | 22 | 67 | 201 | 1 | 0 | 0 | 1 | 21 | 2 | 2 | 3.44 |
| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 31 | 31 | 15 | 10 | 3.80 | .302 | 1.28 | 9.2 | 2.3 | 4.8 | 220.1 | 226 | 98 | 93 | 23 | 57 | 117 | 9 | 0 | 0 | 2 | 18 | 3 | 3 | 4.11 |
| SP | Fernandez, S.Fernandez, Sid >> | 23 | 1985 | L | 49 | 31 | 31 | 15 | 10 | 3.87 | .324 | 1.40 | 7.9 | 4.7 | 7.7 | 193.0 | 169 | 88 | 83 | 19 | 101 | 166 | 2 | 0 | 0 | 0 | 18 | 7 | 1 | 4.24 |
| SP | Lundgren, C.Lundgren, Carl >> | 27 | 1907 | R | 43 | 29 | 29 | 13 | 10 | 4.55 | .337 | 1.52 | 8.9 | 4.8 | 3.7 | 178.0 | 176 | 95 | 90 | 18 | 94 | 74 | 3 | 0 | 0 | 2 | 14 | 2 | 8 | 5.10 |
| RP | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 84 | 0 | 4 | 3 | 3.96 | .304 | 1.30 | 7.9 | 3.9 | 7.8 | 102.1 | 89 | 47 | 45 | 10 | 44 | 88 | 0 | 15 | 3 | 0 | 0 | 1 | 6 | 3.87 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 83 | 55 | 0 | 3 | 3 | 2.71 | .280 | 1.15 | 5.4 | 4.9 | 8.6 | 73.0 | 44 | 23 | 22 | 3 | 40 | 70 | 0 | 2 | 3 | 0 | 0 | 1 | 0 | 3.30 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 46 | 0 | 3 | 6 | 2.94 | .288 | 1.17 | 5.2 | 5.4 | 7.4 | 52.0 | 30 | 17 | 17 | 3 | 31 | 43 | 0 | 4 | 2 | 0 | 0 | 2 | 1 | 4.00 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 37 | 0 | 2 | 2 | 4.46 | .347 | 1.57 | 8.0 | 6.3 | 4.8 | 36.1 | 32 | 19 | 18 | 2 | 25 | 19 | 0 | 3 | 2 | 0 | 0 | 1 | 3 | 4.83 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 38 | 0 | 3 | 3 | 3.77 | .268 | 1.10 | 6.0 | 3.9 | 4.8 | 62.0 | 41 | 27 | 26 | 8 | 27 | 33 | 0 | 1 | 0 | 0 | 0 | 0 | 4 | 4.92 |