| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 16 | 16 | 6 | 5 | 4.08 | .308 | 1.30 | 9.2 | 2.5 | 9.5 | 108.0 | 110 | 51 | 49 | 13 | 30 | 114 | 2 | 0 | 0 | 1 | 9 | 4 | 1 | 3.40 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 16 | 16 | 2 | 8 | 5.34 | .314 | 1.35 | 8.7 | 3.5 | 8.4 | 97.2 | 94 | 59 | 58 | 14 | 38 | 91 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.24 |
| SP | Cueto, J.Cueto, Johnny # >> | 28 | 2014 | R | 75 | 15 | 15 | 4 | 6 | 4.13 | .311 | 1.35 | 8.4 | 3.8 | 6.4 | 104.2 | 97 | 53 | 48 | 12 | 44 | 74 | 3 | 0 | 0 | 1 | 8 | 1 | 2 | 4.38 |
| SP | Waddell, R.Waddell, Rube >> | 29 | 1905 | L | 66 | 15 | 15 | 7 | 5 | 3.54 | .304 | 1.31 | 8.7 | 3.1 | 6.7 | 109.1 | 105 | 44 | 43 | 14 | 38 | 81 | 4 | 0 | 0 | 1 | 8 | 0 | 1 | 4.23 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 40 | 0 | 3 | 3 | 3.83 | .328 | 1.44 | 9.5 | 3.5 | 8.0 | 54.0 | 57 | 25 | 23 | 5 | 21 | 48 | 0 | 4 | 5 | 0 | 0 | 1 | 3 | 3.65 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 74 | 35 | 0 | 2 | 1 | 4.03 | .287 | 1.19 | 7.6 | 3.3 | 9.4 | 44.2 | 37 | 24 | 20 | 4 | 16 | 46 | 0 | 4 | 2 | 0 | 0 | 1 | 0 | 3.25 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 64 | 29 | 0 | 2 | 5 | 4.10 | .277 | 1.13 | 6.6 | 3.6 | 8.0 | 37.1 | 27 | 19 | 17 | 6 | 15 | 33 | 0 | 1 | 1 | 0 | 0 | 1 | 1 | 4.62 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Chesbro, J.Chesbro, Jack >> | 30 | 1904 | R | 65 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 58 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |