| SP | Martinez, P.Martinez, Pedro # >> | 29 | 2000 | R | 100 | 32 | 32 | 15 | 12 | 3.26 | .261 | 1.04 | 7.0 | 2.4 | 8.6 | 232.0 | 181 | 93 | 84 | 25 | 61 | 222 | 7 | 0 | 0 | 1 | 22 | 4 | 3 | 3.33 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 90 | 29 | 29 | 8 | 12 | 4.15 | .290 | 1.20 | 8.1 | 2.8 | 8.7 | 188.2 | 169 | 104 | 87 | 27 | 58 | 182 | 1 | 0 | 0 | 1 | 12 | 4 | 2 | 3.92 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 72 | 25 | 24 | 8 | 7 | 5.23 | .332 | 1.47 | 10.1 | 3.2 | 4.5 | 134.1 | 150 | 87 | 78 | 20 | 48 | 67 | 1 | 0 | 0 | 0 | 13 | 2 | 3 | 5.06 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 30 | 29 | 5 | 14 | 5.94 | .336 | 1.50 | 9.9 | 3.6 | 4.7 | 133.1 | 147 | 91 | 88 | 25 | 53 | 70 | 0 | 0 | 0 | 0 | 9 | 2 | 3 | 5.63 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 72 | 0 | 4 | 3 | 3.05 | .283 | 1.17 | 8.5 | 2.1 | 7.1 | 76.2 | 72 | 30 | 26 | 9 | 18 | 60 | 0 | 2 | 1 | 0 | 0 | 1 | 0 | 3.71 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 62 | 0 | 5 | 3 | 3.88 | .322 | 1.43 | 6.9 | 6.0 | 9.9 | 67.1 | 51 | 34 | 29 | 9 | 45 | 74 | 0 | 2 | 2 | 0 | 0 | 0 | 0 | 4.55 |
| RP | Hernandez, W.Hernandez, Willie >> | 30 | 1984 | L | 44 | 78 | 0 | 4 | 2 | 2.92 | .273 | 1.13 | 7.3 | 2.9 | 6.2 | 52.1 | 42 | 21 | 17 | 5 | 17 | 36 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 3.85 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 28 | 0 | 1 | 2 | 5.06 | .292 | 1.24 | 9.7 | 1.7 | 8.0 | 26.2 | 28 | 15 | 15 | 6 | 5 | 23 | 0 | 0 | 1 | 0 | 0 | 0 | 2 | 4.81 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 68 | 31 | 0 | 3 | 1 | 5.30 | .317 | 1.39 | 9.7 | 2.9 | 4.6 | 37.1 | 40 | 26 | 22 | 6 | 12 | 19 | 0 | 2 | 1 | 0 | 0 | 0 | 1 | 5.05 |
| CL | Betances, D.Betances, Dellin † >> | 26 | 2014 | R | 93 | 64 | 0 | 4 | 6 | 3.08 | .303 | 1.31 | 7.6 | 4.2 | 9.7 | 64.1 | 54 | 23 | 22 | 8 | 30 | 69 | 0 | 32 | 5 | 0 | 0 | 0 | 5 | 3.88 |
| SP | Carlton, S.Carlton, Steve >> | 28 | 1972 | L | 51 | 17 | 2 | 1 | 0 | 4.37 | .313 | 1.37 | 9.1 | 3.2 | 6.9 | 68.0 | 69 | 43 | 33 | 7 | 24 | 52 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 3.87 |