| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 93 | 13 | 13 | 5 | 4 | 3.36 | .283 | 1.17 | 7.9 | 2.7 | 7.7 | 80.1 | 70 | 33 | 30 | 10 | 24 | 68 | 1 | 0 | 0 | 0 | 9 | 1 | 0 | 3.86 |
| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 11 | 11 | 5 | 2 | 3.63 | .308 | 1.33 | 8.8 | 3.3 | 4.1 | 72.0 | 70 | 31 | 29 | 3 | 26 | 33 | 0 | 0 | 0 | 0 | 8 | 0 | 1 | 3.71 |
| SP | Mathewson, C.Mathewson, Christy >> | 29 | 1909 | R | 85 | 12 | 12 | 5 | 1 | 2.61 | .251 | 0.98 | 7.7 | 1.2 | 3.7 | 89.2 | 76 | 28 | 26 | 7 | 12 | 37 | 3 | 0 | 0 | 2 | 9 | 2 | 0 | 3.66 |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 76 | 12 | 12 | 5 | 4 | 5.13 | .309 | 1.34 | 9.2 | 3.0 | 6.8 | 73.2 | 75 | 42 | 42 | 14 | 24 | 55 | 0 | 0 | 0 | 0 | 5 | 0 | 0 | 4.97 |
| RP | Doolittle, S.Doolittle, Sean >> | 31 | 2018 | L | 99 | 31 | 0 | 2 | 3 | 3.59 | .269 | 1.10 | 5.6 | 4.5 | 6.0 | 42.2 | 26 | 17 | 17 | 2 | 21 | 28 | 0 | 3 | 4 | 0 | 0 | 0 | 2 | 3.79 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 25 | 0 | 3 | 1 | 3.04 | .252 | 1.01 | 5.5 | 3.8 | 8.7 | 26.2 | 16 | 9 | 9 | 2 | 11 | 25 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 3.35 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 77 | 12 | 0 | 3 | 0 | 0.63 | .189 | 0.70 | 5.1 | 1.3 | 8.4 | 14.1 | 8 | 1 | 1 | 0 | 2 | 13 | 0 | 2 | 0 | 0 | 0 | 0 | 2 | 1.57 |
| RP | Broxton, J.Broxton, Jonathan >> | 25 | 2009 | R | 61 | 3 | 0 | 0 | 0 | 0.00 | .286 | 1.20 | 9.0 | 9.0 | 18.0 | 1.2 | 1 | 0 | 0 | 0 | 1 | 2 | 0 | 3 | 0 | 0 | 0 | 0 | 0 | 2.00 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 48 | 8 | 0 | 1 | 0 | 4.41 | .300 | 1.29 | 7.3 | 4.5 | 9.6 | 16.1 | 13 | 8 | 8 | 3 | 8 | 17 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.81 |