| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 32 | 32 | 12 | 7 | 2.84 | .245 | 0.96 | 6.2 | 2.4 | 8.2 | 225.0 | 155 | 73 | 71 | 26 | 60 | 205 | 2 | 0 | 0 | 2 | 24 | 4 | 0 | 3.53 |
| SP | Marichal, J.Marichal, Juan >> | 29 | 1966 | R | 77 | 30 | 30 | 8 | 15 | 5.35 | .327 | 1.44 | 10.2 | 2.8 | 4.9 | 208.2 | 236 | 134 | 124 | 36 | 65 | 113 | 9 | 0 | 0 | 1 | 10 | 3 | 2 | 5.14 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 55 | 0 | 6 | 3 | 3.25 | .287 | 1.18 | 7.3 | 3.4 | 9.6 | 63.2 | 51 | 23 | 23 | 5 | 24 | 67 | 0 | 8 | 4 | 0 | 0 | 2 | 0 | 3.14 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 85 | 32 | 0 | 3 | 5 | 5.06 | .324 | 1.38 | 9.8 | 2.5 | 10.7 | 32.0 | 35 | 18 | 18 | 5 | 9 | 38 | 0 | 6 | 1 | 0 | 0 | 2 | 1 | 3.69 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 76 | 20 | 0 | 3 | 3 | 3.91 | .315 | 1.38 | 7.6 | 5.0 | 8.3 | 25.1 | 21 | 13 | 11 | 2 | 14 | 23 | 0 | 1 | 1 | 0 | 0 | 0 | 2 | 3.88 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 27 | 0 | 1 | 2 | 2.97 | .283 | 1.19 | 7.2 | 3.6 | 6.3 | 30.1 | 24 | 10 | 10 | 4 | 12 | 21 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 4.53 |