| SP | Scherzer, M.Scherzer, Max # >> | 33 | 2017 | R | 95 | 28 | 28 | 12 | 9 | 3.71 | .277 | 1.14 | 7.2 | 3.0 | 8.0 | 189.1 | 151 | 78 | 78 | 26 | 64 | 169 | 1 | 0 | 0 | 0 | 19 | 3 | 6 | 4.06 |
| SP | Hernandez, F.Hernandez, Felix >> | 28 | 2014 | R | 79 | 28 | 28 | 7 | 19 | 4.92 | .323 | 1.40 | 9.2 | 3.4 | 6.9 | 184.2 | 189 | 111 | 101 | 28 | 69 | 141 | 3 | 0 | 0 | 0 | 11 | 6 | 13 | 4.67 |
| SP | Clemens, R.Clemens, Roger >> | 24 | 1986 | R | 69 | 27 | 27 | 12 | 10 | 4.29 | .292 | 1.23 | 7.5 | 3.5 | 5.7 | 195.0 | 163 | 94 | 93 | 26 | 76 | 123 | 10 | 0 | 0 | 0 | 14 | 2 | 6 | 4.67 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 61 | 26 | 26 | 9 | 7 | 4.70 | .325 | 1.41 | 7.8 | 4.9 | 8.4 | 128.1 | 111 | 70 | 67 | 16 | 70 | 120 | 0 | 0 | 0 | 0 | 6 | 4 | 2 | 4.48 |
| SP | Hudson, D.Hudson, Daniel # >> | 23 | 2010 | R | 60 | 27 | 27 | 4 | 14 | 6.31 | .347 | 1.57 | 10.1 | 4.0 | 5.0 | 157.0 | 177 | 111 | 110 | 24 | 69 | 88 | 0 | 0 | 0 | 0 | 8 | 4 | 7 | 5.26 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 90 | 0 | 2 | 5 | 2.64 | .288 | 1.19 | 6.4 | 4.3 | 8.8 | 75.0 | 53 | 26 | 22 | 8 | 36 | 73 | 0 | 5 | 1 | 0 | 0 | 2 | 1 | 3.96 |
| RP | Williams, D.Williams, Devin >> | 28 | 2023 | R | 74 | 76 | 0 | 7 | 3 | 3.27 | .310 | 1.32 | 6.2 | 5.7 | 9.0 | 85.1 | 59 | 32 | 31 | 8 | 54 | 85 | 0 | 3 | 2 | 0 | 0 | 2 | 0 | 4.20 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 41 | 0 | 1 | 0 | 2.09 | .257 | 1.04 | 6.5 | 2.9 | 7.5 | 47.1 | 34 | 11 | 11 | 5 | 15 | 39 | 0 | 4 | 0 | 0 | 0 | 0 | 1 | 3.68 |
| SP | McGinnity, J.McGinnity, Joe >> | 33 | 1904 | R | 50 | 13 | 1 | 1 | 2 | 6.27 | .356 | 1.66 | 12.5 | 3.0 | 3.0 | 18.2 | 25 | 13 | 13 | 3 | 6 | 6 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 5.50 |