| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 13 | 13 | 7 | 6 | 4.33 | .307 | 1.30 | 7.9 | 3.9 | 8.1 | 79.0 | 69 | 41 | 38 | 7 | 34 | 71 | 0 | 0 | 0 | 0 | 8 | 2 | 1 | 3.72 |
| SP | Greinke, Z.Greinke, Zack >> | 32 | 2015 | R | 94 | 12 | 12 | 5 | 6 | 4.73 | .316 | 1.36 | 9.5 | 2.8 | 6.8 | 80.0 | 84 | 46 | 42 | 11 | 25 | 60 | 4 | 0 | 0 | 0 | 7 | 2 | 4 | 4.30 |
| SP | Santana, J.Santana, Johan >> | 25 | 2004 | L | 86 | 12 | 12 | 5 | 6 | 4.38 | .278 | 1.12 | 7.8 | 2.2 | 7.7 | 78.0 | 68 | 38 | 38 | 12 | 19 | 67 | 0 | 0 | 0 | 0 | 7 | 3 | 2 | 4.13 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 12 | 12 | 4 | 3 | 4.65 | .298 | 1.24 | 8.5 | 2.6 | 3.3 | 79.1 | 75 | 42 | 41 | 11 | 23 | 29 | 3 | 0 | 0 | 0 | 5 | 3 | 3 | 5.06 |
| SP | Hernandez, F.Hernandez, Felix # >> | 28 | 2014 | R | 80 | 12 | 12 | 4 | 7 | 3.81 | .281 | 1.16 | 7.6 | 2.9 | 7.3 | 89.2 | 75 | 41 | 38 | 11 | 29 | 72 | 1 | 0 | 0 | 1 | 5 | 1 | 2 | 4.00 |
| RP | Uehara, K.Uehara, Koji >> | 38 | 2013 | R | 100 | 32 | 0 | 1 | 0 | 2.63 | .226 | 0.88 | 6.3 | 1.7 | 11.7 | 37.2 | 26 | 11 | 11 | 3 | 7 | 48 | 0 | 6 | 0 | 0 | 0 | 0 | 0 | 2.03 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 87 | 20 | 0 | 4 | 2 | 6.45 | .330 | 1.48 | 11.5 | 2.0 | 6.5 | 22.1 | 28 | 16 | 16 | 3 | 5 | 16 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.00 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 8 | 0 | 0 | 0 | 13.50 | .484 | 2.81 | 10.8 | 16.2 | 10.8 | 5.1 | 6 | 11 | 8 | 3 | 9 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 13.80 |
| RP | Pagan, E.Pagan, Emilio >> | 28 | 2019 | R | 76 | 8 | 0 | 0 | 0 | 4.05 | .375 | 1.80 | 13.5 | 4.5 | 7.5 | 6.2 | 9 | 5 | 3 | 1 | 3 | 5 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 5.00 |
| RP | Betancourt, R.Betancourt, Rafael >> | 32 | 2007 | R | 77 | 8 | 0 | 0 | 0 | 6.00 | .341 | 1.56 | 9.0 | 5.0 | 9.0 | 9.0 | 9 | 6 | 6 | 0 | 5 | 9 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.67 |
| SP | Tanana, F.Tanana, Frank >> | 23 | 1976 | L | 55 | 7 | 0 | 1 | 0 | 5.22 | .331 | 1.49 | 11.3 | 2.3 | 6.2 | 39.2 | 49 | 25 | 23 | 6 | 10 | 27 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 4.38 |