| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 95 | 34 | 34 | 16 | 13 | 4.07 | .300 | 1.26 | 7.7 | 3.6 | 8.7 | 219.0 | 188 | 103 | 99 | 21 | 87 | 212 | 2 | 0 | 0 | 0 | 22 | 7 | 3 | 3.60 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 60 | 32 | 32 | 8 | 12 | 5.10 | .332 | 1.47 | 8.8 | 4.5 | 6.1 | 185.1 | 180 | 108 | 105 | 27 | 92 | 125 | 0 | 0 | 0 | 0 | 16 | 4 | 12 | 5.10 |
| SP | Russell, R.Russell, Reb >> | 27 | 1916 | L | 53 | 32 | 32 | 11 | 9 | 4.55 | .298 | 1.26 | 8.9 | 2.4 | 3.9 | 150.1 | 149 | 82 | 76 | 19 | 40 | 65 | 0 | 0 | 0 | 0 | 6 | 2 | 1 | 4.62 |
| SP | Cuellar, M.Cuellar, Mike >> | 32 | 1969 | L | 44 | 33 | 31 | 10 | 12 | 5.77 | .346 | 1.55 | 9.7 | 4.3 | 5.2 | 202.2 | 217 | 143 | 130 | 26 | 97 | 117 | 2 | 0 | 0 | 1 | 9 | 7 | 6 | 5.06 |
| RP | Street, H.Street, Huston >> | 29 | 2012 | R | 96 | 102 | 0 | 7 | 6 | 3.25 | .291 | 1.21 | 7.3 | 3.6 | 8.9 | 130.0 | 105 | 49 | 47 | 11 | 52 | 128 | 0 | 10 | 4 | 0 | 0 | 3 | 5 | 3.40 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 68 | 93 | 0 | 4 | 4 | 4.07 | .318 | 1.39 | 8.3 | 4.3 | 7.6 | 121.2 | 111 | 57 | 55 | 14 | 58 | 102 | 0 | 7 | 1 | 0 | 0 | 1 | 2 | 4.28 |
| RP | Williamson, S.Williamson, Scott >> | 23 | 1999 | R | 45 | 51 | 0 | 2 | 1 | 6.04 | .367 | 1.72 | 10.4 | 5.2 | 9.4 | 50.2 | 58 | 37 | 34 | 5 | 29 | 52 | 0 | 4 | 2 | 0 | 0 | 1 | 5 | 4.02 |