| SP | McNally, D.McNally, Dave >> | 26 | 1968 | L | 96 | 34 | 34 | 16 | 10 | 3.96 | .297 | 1.25 | 8.2 | 3.0 | 5.8 | 236.1 | 216 | 116 | 104 | 27 | 79 | 151 | 10 | 0 | 0 | 3 | 18 | 5 | 8 | 4.28 |
| SP | Pfiester, J.Pfiester, Jack # >> | 28 | 1906 | L | 74 | 32 | 32 | 10 | 18 | 4.99 | .336 | 1.48 | 10.1 | 3.3 | 4.9 | 220.0 | 246 | 129 | 122 | 24 | 80 | 120 | 8 | 0 | 0 | 1 | 16 | 8 | 6 | 4.53 |
| SP | Bender, C.Bender, Chief >> | 26 | 1910 | R | 72 | 31 | 31 | 15 | 9 | 4.17 | .294 | 1.22 | 8.3 | 2.7 | 5.6 | 233.1 | 216 | 119 | 108 | 28 | 69 | 145 | 12 | 0 | 0 | 2 | 15 | 6 | 4 | 4.28 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 76 | 0 | 7 | 6 | 3.71 | .284 | 1.19 | 7.6 | 3.2 | 9.2 | 106.2 | 89 | 46 | 44 | 14 | 38 | 108 | 0 | 4 | 3 | 0 | 0 | 0 | 6 | 3.75 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 70 | 0 | 8 | 5 | 3.22 | .277 | 1.12 | 7.4 | 2.7 | 5.5 | 128.2 | 105 | 50 | 46 | 13 | 39 | 78 | 0 | 9 | 2 | 0 | 0 | 4 | 6 | 4.11 |
| RP | Wuertz, M.Wuertz, Michael >> | 31 | 2009 | R | 56 | 33 | 0 | 2 | 0 | 2.27 | .340 | 1.54 | 9.0 | 5.1 | 8.2 | 35.2 | 35 | 12 | 9 | 3 | 20 | 32 | 0 | 4 | 0 | 0 | 0 | 0 | 3 | 4.00 |
| RP | Abernathy, T.Abernathy, Ted >> | 34 | 1967 | R | 49 | 23 | 0 | 1 | 2 | 3.38 | .258 | 1.04 | 5.4 | 4.1 | 4.4 | 37.1 | 22 | 14 | 14 | 3 | 17 | 18 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.46 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 55 | 1 | 1 | 0 | 0 | 16.88 | .500 | 3.00 | 27.0 | 9.0 | 9.0 | 2.2 | 6 | 5 | 5 | 1 | 2 | 2 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 10.50 |
| SP | Coveleski, S.Coveleski, Stan >> | 28 | 1917 | R | 62 | 1 | 0 | 0 | 0 | 9.00 | .400 | 2.00 | 18.0 | 0.0 | 0.0 | 1.0 | 2 | 1 | 1 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.00 |
| SP | McQuillan, G.McQuillan, George >> | 23 | 1908 | R | 48 | 11 | 0 | 1 | 4 | 3.48 | .340 | 1.55 | 10.8 | 3.6 | 6.3 | 20.2 | 24 | 9 | 8 | 2 | 8 | 14 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.10 |