| SP | Maddux, G.Maddux, Greg >> | 29 | 1995 | R | 89 | 31 | 31 | 9 | 11 | 4.15 | .307 | 1.32 | 9.2 | 2.6 | 6.0 | 219.0 | 225 | 106 | 101 | 25 | 63 | 147 | 5 | 0 | 0 | 2 | 15 | 3 | 1 | 4.05 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 85 | 32 | 32 | 11 | 11 | 6.07 | .334 | 1.47 | 10.5 | 2.8 | 4.7 | 163.0 | 190 | 112 | 110 | 35 | 50 | 85 | 0 | 0 | 0 | 0 | 3 | 5 | 6 | 5.76 |
| SP | Cicotte, E.Cicotte, Eddie >> | 33 | 1917 | R | 74 | 32 | 32 | 12 | 12 | 4.25 | .317 | 1.36 | 9.1 | 3.1 | 5.2 | 235.1 | 238 | 116 | 111 | 25 | 82 | 135 | 5 | 0 | 0 | 2 | 15 | 7 | 1 | 4.37 |
| RP | Wagner, B.Wagner, Billy >> | 28 | 1999 | L | 95 | 87 | 0 | 4 | 6 | 4.07 | .307 | 1.27 | 7.5 | 4.0 | 8.8 | 110.2 | 92 | 51 | 50 | 15 | 49 | 107 | 0 | 9 | 7 | 0 | 0 | 6 | 1 | 4.33 |
| RP | Eckersley, D.Eckersley, Dennis >> | 36 | 1990 | R | 88 | 72 | 0 | 8 | 3 | 2.91 | .234 | 0.89 | 6.3 | 1.7 | 8.3 | 96.0 | 67 | 33 | 31 | 8 | 18 | 88 | 0 | 4 | 2 | 0 | 0 | 3 | 0 | 2.91 |
| RP | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 82 | 57 | 0 | 5 | 3 | 3.26 | .255 | 1.03 | 6.4 | 2.9 | 4.6 | 69.0 | 49 | 30 | 25 | 11 | 22 | 35 | 0 | 8 | 3 | 0 | 0 | 0 | 0 | 5.01 |
| RP | Wilson, B.Wilson, Brian >> | 28 | 2010 | R | 7 | 34 | 0 | 1 | 5 | 9.79 | .452 | 2.48 | 14.5 | 8.3 | 9.7 | 26.2 | 42 | 30 | 29 | 5 | 24 | 28 | 0 | 2 | 3 | 0 | 0 | 0 | 0 | 6.12 |
| RP | Righetti, D.Righetti, Dave >> | 28 | 1986 | L | 3 | 33 | 0 | 2 | 0 | 5.13 | .366 | 1.71 | 10.8 | 4.7 | 5.2 | 40.1 | 48 | 24 | 23 | 3 | 21 | 23 | 0 | 1 | 1 | 0 | 0 | 1 | 0 | 4.48 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 2 | 2 | 0 | 1 | 3.38 | .322 | 1.35 | 9.7 | 2.8 | 3.5 | 13.1 | 14 | 5 | 5 | 0 | 4 | 5 | 0 | 0 | 0 | 0 | 1 | 1 | 0 | 3.38 |