| SP | Koufax, S.Koufax, Sandy † >> | 30 | 1965 | L | 97 | 35 | 35 | 21 | 7 | 2.62 | .248 | 0.98 | 6.3 | 2.6 | 7.2 | 250.1 | 174 | 74 | 73 | 19 | 71 | 201 | 8 | 0 | 0 | 3 | 27 | 3 | 4 | 3.27 |
| SP | Mathewson, C.Mathewson, Christy † >> | 29 | 1909 | R | 86 | 34 | 34 | 19 | 10 | 2.99 | .252 | 0.99 | 6.8 | 2.1 | 4.3 | 229.0 | 174 | 80 | 76 | 18 | 53 | 110 | 4 | 0 | 0 | 3 | 24 | 4 | 3 | 3.81 |
| SP | Alexander, P.Alexander, Pete † >> | 28 | 1915 | R | 88 | 33 | 33 | 17 | 7 | 3.80 | .273 | 1.11 | 7.6 | 2.4 | 5.1 | 211.0 | 178 | 92 | 89 | 20 | 57 | 119 | 5 | 0 | 0 | 2 | 21 | 3 | 4 | 3.96 |
| SP | Snell, B.Snell, Blake $ >> | 25 | 2018 | L | 81 | 32 | 32 | 17 | 9 | 3.41 | .283 | 1.15 | 6.1 | 4.2 | 8.0 | 221.2 | 151 | 87 | 84 | 27 | 104 | 197 | 4 | 0 | 0 | 0 | 19 | 8 | 10 | 4.33 |
| CL | Chapman, A.Chapman, Aroldis † >> | 26 | 2014 | L | 94 | 88 | 0 | 8 | 2 | 3.39 | .287 | 1.19 | 5.1 | 5.6 | 8.8 | 101.0 | 57 | 39 | 38 | 8 | 63 | 99 | 0 | 12 | 2 | 0 | 0 | 2 | 9 | 4.00 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 88 | 45 | 0 | 4 | 3 | 3.59 | .296 | 1.26 | 7.3 | 4.2 | 8.2 | 47.2 | 38 | 19 | 19 | 8 | 22 | 43 | 0 | 9 | 2 | 0 | 0 | 0 | 3 | 4.79 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 72 | 38 | 0 | 3 | 2 | 3.71 | .288 | 1.17 | 7.3 | 3.3 | 9.2 | 43.2 | 35 | 18 | 18 | 6 | 16 | 44 | 0 | 3 | 0 | 0 | 0 | 2 | 1 | 4.02 |
| RP | Smoltz, J.Smoltz, John >> | 36 | 2003 | R | 52 | 8 | 0 | 0 | 0 | 1.93 | .243 | 0.96 | 7.0 | 2.0 | 11.0 | 9.1 | 7 | 2 | 2 | 1 | 2 | 11 | 0 | 1 | 0 | 0 | 0 | 0 | 1 | 2.67 |
| RP | Eichhorn, M.Eichhorn, Mark >> | 26 | 1986 | R | 49 | 6 | 0 | 0 | 0 | 2.25 | .234 | 0.92 | 4.5 | 3.8 | 8.3 | 12.0 | 6 | 3 | 3 | 1 | 5 | 11 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |