| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 11 | 13 | 3.89 | .301 | 1.28 | 8.8 | 2.7 | 9.3 | 194.1 | 190 | 92 | 84 | 26 | 58 | 200 | 0 | 0 | 0 | 0 | 19 | 3 | 0 | 3.62 |
| SP | Cole, G.Cole, Gerrit # >> | 28 | 2019 | R | 92 | 35 | 35 | 13 | 11 | 4.36 | .297 | 1.25 | 8.7 | 2.6 | 9.7 | 206.1 | 198 | 109 | 100 | 22 | 60 | 221 | 2 | 0 | 0 | 0 | 21 | 4 | 5 | 3.17 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 36 | 35 | 8 | 17 | 6.39 | .360 | 1.67 | 10.8 | 4.2 | 5.1 | 174.2 | 209 | 139 | 124 | 30 | 82 | 98 | 2 | 0 | 0 | 0 | 12 | 4 | 6 | 5.60 |
| SP | Cueto, J.Cueto, Johnny >> | 28 | 2014 | R | 75 | 33 | 33 | 12 | 9 | 5.30 | .336 | 1.50 | 9.6 | 3.9 | 5.2 | 181.2 | 193 | 117 | 107 | 26 | 79 | 105 | 1 | 0 | 0 | 0 | 14 | 4 | 2 | 5.08 |
| CL | Kimbrel, C.Kimbrel, Craig >> | 24 | 2012 | R | 100 | 95 | 0 | 2 | 17 | 4.58 | .319 | 1.40 | 7.8 | 4.8 | 10.3 | 106.0 | 92 | 60 | 54 | 13 | 56 | 121 | 0 | 29 | 11 | 0 | 0 | 1 | 9 | 3.92 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 102 | 0 | 6 | 5 | 3.95 | .313 | 1.35 | 7.9 | 4.3 | 9.6 | 118.1 | 103 | 57 | 52 | 16 | 57 | 126 | 0 | 0 | 5 | 0 | 0 | 2 | 0 | 4.13 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 83 | 108 | 0 | 6 | 4 | 5.12 | .325 | 1.43 | 8.4 | 4.5 | 9.7 | 123.0 | 115 | 73 | 70 | 16 | 61 | 133 | 0 | 1 | 1 | 0 | 0 | 2 | 5 | 4.07 |
| RP | Devine, J.Devine, Joey >> | 25 | 2008 | R | 80 | 97 | 0 | 4 | 2 | 2.88 | .321 | 1.38 | 8.0 | 4.5 | 8.2 | 112.2 | 99 | 44 | 36 | 12 | 56 | 102 | 0 | 4 | 1 | 0 | 0 | 5 | 0 | 4.21 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 75 | 75 | 0 | 4 | 3 | 3.73 | .298 | 1.26 | 6.1 | 5.3 | 9.7 | 101.1 | 69 | 47 | 42 | 12 | 59 | 109 | 0 | 2 | 4 | 0 | 0 | 1 | 5 | 4.17 |