| SP | Martinez, P.Martinez, Pedro † >> | 29 | 2000 | R | 100 | 35 | 35 | 16 | 11 | 3.29 | .270 | 1.10 | 7.4 | 2.5 | 8.8 | 252.0 | 207 | 93 | 92 | 25 | 71 | 247 | 7 | 0 | 0 | 4 | 23 | 1 | 2 | 3.19 |
| SP | Maddux, G.Maddux, Greg † >> | 29 | 1995 | R | 90 | 34 | 34 | 12 | 9 | 3.25 | .257 | 1.02 | 7.3 | 1.9 | 6.5 | 243.1 | 197 | 88 | 88 | 36 | 51 | 176 | 5 | 0 | 0 | 3 | 23 | 4 | 2 | 4.16 |
| CL | Rodney, F.Rodney, Fernando † >> | 35 | 2012 | R | 79 | 58 | 0 | 5 | 7 | 2.53 | .250 | 0.98 | 5.1 | 3.8 | 7.5 | 64.0 | 36 | 19 | 18 | 3 | 27 | 53 | 0 | 33 | 4 | 0 | 0 | 1 | 1 | 3.27 |
| SU | Betancourt, R.Betancourt, Rafael # >> | 32 | 2007 | R | 75 | 38 | 0 | 1 | 3 | 4.82 | .287 | 1.18 | 8.0 | 2.7 | 6.8 | 37.1 | 33 | 20 | 20 | 6 | 11 | 28 | 0 | 6 | 7 | 0 | 0 | 1 | 0 | 4.57 |
| RP | Hoffman, T.Hoffman, Trevor >> | 31 | 1998 | R | 72 | 63 | 0 | 3 | 3 | 2.95 | .297 | 1.27 | 6.9 | 4.5 | 9.4 | 64.0 | 49 | 21 | 21 | 11 | 32 | 67 | 0 | 3 | 1 | 0 | 0 | 0 | 1 | 4.64 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 65 | 23 | 0 | 5 | 1 | 1.77 | .282 | 1.18 | 8.1 | 2.7 | 10.8 | 20.1 | 18 | 5 | 4 | 1 | 6 | 24 | 0 | 0 | 0 | 0 | 0 | 0 | 1 | 2.15 |