| SP | Johnson, R.Johnson, Randy >> | 41 | 2004 | L | 89 | 34 | 34 | 9 | 18 | 4.19 | .317 | 1.36 | 8.7 | 3.5 | 9.8 | 227.2 | 220 | 115 | 106 | 29 | 89 | 248 | 2 | 0 | 0 | 0 | 16 | 8 | 2 | 3.76 |
| SP | Maddux, G.Maddux, Greg # >> | 29 | 1995 | R | 90 | 33 | 33 | 16 | 14 | 3.97 | .299 | 1.26 | 9.3 | 2.0 | 6.2 | 247.1 | 256 | 119 | 109 | 25 | 56 | 169 | 5 | 0 | 0 | 2 | 18 | 5 | 2 | 3.69 |
| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 84 | 32 | 32 | 10 | 12 | 4.45 | .349 | 1.58 | 10.0 | 4.2 | 9.6 | 174.0 | 194 | 94 | 86 | 23 | 81 | 185 | 0 | 0 | 0 | 0 | 12 | 5 | 0 | 4.07 |
| SP | McNally, D.McNally, Dave >> | 29 | 1971 | L | 16 | 17 | 17 | 6 | 9 | 4.70 | .335 | 1.49 | 10.5 | 2.8 | 5.6 | 111.0 | 130 | 64 | 58 | 21 | 35 | 69 | 2 | 0 | 0 | 0 | 9 | 3 | 3 | 5.24 |
| SP | Perez, P.Perez, Pascual # >> | 31 | 1988 | R | 76 | 30 | 30 | 13 | 10 | 4.94 | .316 | 1.35 | 8.9 | 3.3 | 6.0 | 191.1 | 188 | 110 | 105 | 23 | 71 | 127 | 5 | 0 | 0 | 1 | 15 | 6 | 5 | 4.45 |
| RP | Saito, T.Saito, Takashi >> | 37 | 2007 | R | 90 | 86 | 0 | 3 | 3 | 3.19 | .318 | 1.36 | 8.1 | 4.2 | 10.4 | 101.2 | 91 | 37 | 36 | 14 | 47 | 117 | 0 | 8 | 5 | 0 | 0 | 4 | 0 | 4.00 |
| RP | Sutter, B.Sutter, Bruce >> | 24 | 1977 | R | 65 | 38 | 0 | 1 | 0 | 4.20 | .353 | 1.60 | 10.5 | 3.9 | 13.2 | 30.0 | 35 | 16 | 14 | 4 | 13 | 44 | 0 | 4 | 0 | 0 | 0 | 1 | 4 | 3.20 |
| RP | Gossage, R.Gossage, Rich >> | 30 | 1981 | R | 88 | 36 | 0 | 3 | 3 | 4.54 | .323 | 1.43 | 9.2 | 3.9 | 10.5 | 37.2 | 38 | 19 | 19 | 4 | 16 | 43 | 0 | 5 | 1 | 0 | 0 | 0 | 1 | 3.38 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 83 | 22 | 0 | 2 | 0 | 5.85 | .381 | 1.75 | 12.6 | 3.2 | 8.1 | 20.0 | 28 | 14 | 13 | 0 | 7 | 18 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 2.55 |
| SP | Blyleven, B.Blyleven, Bert >> | 26 | 1977 | R | 37 | 0 | 0 | 0 | 0 | - | .000 | - | - | - | - | 0.0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | - |
| SP | Fernandez, J.Fernandez, Jose # >> | 21 | 2013 | R | 83 | 18 | 1 | 4 | 1 | 6.53 | .391 | 1.90 | 11.4 | 5.8 | 8.9 | 71.2 | 90 | 54 | 52 | 18 | 46 | 70 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 6.35 |