| SP | deGrom, J.deGrom, Jacob >> | 33 | 2021 | R | 100 | 34 | 34 | 13 | 8 | 3.19 | .264 | 1.06 | 7.2 | 2.4 | 9.5 | 220.0 | 175 | 80 | 78 | 33 | 58 | 232 | 1 | 0 | 0 | 0 | 26 | 4 | 0 | 3.69 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 33 | 32 | 7 | 19 | 6.11 | .348 | 1.56 | 10.4 | 3.7 | 8.5 | 157.2 | 182 | 116 | 107 | 34 | 64 | 149 | 0 | 0 | 0 | 0 | 12 | 6 | 6 | 5.25 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 67 | 32 | 31 | 8 | 15 | 4.77 | .318 | 1.37 | 9.2 | 3.2 | 6.3 | 205.2 | 209 | 121 | 109 | 34 | 73 | 143 | 5 | 0 | 0 | 0 | 14 | 6 | 6 | 4.92 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 92 | 0 | 6 | 6 | 4.42 | .316 | 1.37 | 8.2 | 4.1 | 9.8 | 106.0 | 97 | 53 | 52 | 24 | 48 | 115 | 0 | 4 | 2 | 0 | 0 | 2 | 2 | 5.19 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 66 | 67 | 0 | 5 | 3 | 3.24 | .329 | 1.44 | 7.5 | 5.6 | 8.0 | 66.2 | 55 | 24 | 24 | 7 | 41 | 59 | 0 | 2 | 2 | 0 | 0 | 2 | 0 | 4.55 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 66 | 48 | 0 | 3 | 4 | 3.35 | .260 | 1.06 | 5.8 | 3.8 | 6.9 | 48.1 | 31 | 18 | 18 | 11 | 20 | 37 | 0 | 2 | 1 | 0 | 0 | 0 | 3 | 5.69 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 38 | 0 | 2 | 1 | 2.66 | .279 | 1.16 | 6.8 | 3.7 | 11.3 | 44.0 | 33 | 14 | 13 | 4 | 18 | 55 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 2.91 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 67 | 25 | 0 | 6 | 1 | 4.11 | .327 | 1.43 | 7.3 | 5.6 | 8.7 | 92.0 | 75 | 46 | 42 | 14 | 57 | 89 | 0 | 1 | 1 | 0 | 0 | 2 | 3 | 4.97 |
| CL | Uehara, K.Uehara, Koji † >> | 38 | 2013 | R | 100 | 70 | 0 | 5 | 9 | 3.27 | .283 | 1.16 | 7.6 | 2.8 | 9.2 | 77.0 | 65 | 28 | 28 | 10 | 24 | 79 | 0 | 35 | 6 | 0 | 0 | 2 | 1 | 3.65 |