| SP | Scherzer, M.Scherzer, Max >> | 33 | 2017 | R | 97 | 19 | 19 | 5 | 9 | 4.30 | .301 | 1.27 | 8.0 | 3.4 | 10.2 | 121.1 | 108 | 68 | 58 | 14 | 46 | 137 | 2 | 0 | 0 | 1 | 9 | 3 | 4 | 3.45 |
| SP | Schmidt, J.Schmidt, Jason # >> | 30 | 2003 | R | 78 | 19 | 19 | 5 | 6 | 4.15 | .294 | 1.24 | 8.2 | 3.0 | 8.9 | 132.1 | 120 | 67 | 61 | 12 | 44 | 130 | 4 | 0 | 0 | 0 | 11 | 1 | 6 | 3.23 |
| SP | Strasburg, S.Strasburg, Stephen >> | 28 | 2017 | R | 65 | 18 | 18 | 7 | 6 | 4.29 | .319 | 1.38 | 9.1 | 3.3 | 8.3 | 109.0 | 110 | 56 | 52 | 11 | 40 | 100 | 0 | 0 | 0 | 0 | 8 | 3 | 1 | 3.66 |
| SP | Higuera, T.Higuera, Teddy >> | 30 | 1988 | L | 63 | 18 | 18 | 5 | 7 | 5.93 | .321 | 1.40 | 8.8 | 3.8 | 6.5 | 101.2 | 99 | 68 | 67 | 15 | 43 | 73 | 2 | 0 | 0 | 1 | 7 | 2 | 0 | 4.82 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 47 | 0 | 6 | 3 | 3.49 | .298 | 1.24 | 7.9 | 3.3 | 9.9 | 80.0 | 70 | 34 | 31 | 9 | 29 | 88 | 0 | 4 | 5 | 0 | 0 | 3 | 0 | 3.46 |
| RP | Boxberger, B.Boxberger, Brad >> | 26 | 2014 | R | 82 | 41 | 0 | 4 | 2 | 2.45 | .302 | 1.30 | 8.0 | 3.8 | 9.4 | 47.2 | 42 | 13 | 13 | 1 | 20 | 49 | 0 | 3 | 3 | 0 | 0 | 0 | 5 | 2.47 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 41 | 0 | 2 | 1 | 3.44 | .270 | 1.09 | 6.4 | 3.4 | 5.6 | 55.0 | 39 | 22 | 21 | 7 | 21 | 34 | 0 | 2 | 4 | 0 | 0 | 1 | 0 | 4.62 |
| RP | Benitez, A.Benitez, Armando >> | 27 | 1999 | R | 57 | 32 | 0 | 1 | 4 | 6.38 | .337 | 1.50 | 9.3 | 4.5 | 12.0 | 36.2 | 37 | 26 | 26 | 8 | 18 | 48 | 0 | 4 | 3 | 0 | 0 | 1 | 0 | 4.81 |
| SP | Weaver, J.Weaver, Jered >> | 29 | 2011 | R | 52 | 23 | 0 | 5 | 3 | 6.59 | .371 | 1.72 | 11.6 | 4.1 | 7.3 | 42.1 | 54 | 32 | 31 | 9 | 19 | 34 | 0 | 0 | 0 | 0 | 0 | 2 | 1 | 5.67 |