| SP | Martinez, P.Martinez, Pedro >> | 29 | 2000 | R | 100 | 36 | 36 | 18 | 11 | 3.29 | .274 | 1.11 | 7.6 | 2.4 | 9.2 | 254.1 | 214 | 107 | 93 | 28 | 69 | 261 | 6 | 0 | 0 | 3 | 23 | 5 | 3 | 3.25 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 35 | 35 | 9 | 12 | 5.48 | .320 | 1.37 | 9.0 | 3.4 | 7.9 | 180.2 | 179 | 113 | 110 | 43 | 68 | 157 | 0 | 0 | 0 | 0 | 13 | 8 | 9 | 5.63 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 78 | 33 | 33 | 9 | 14 | 5.51 | .317 | 1.38 | 8.9 | 3.5 | 7.7 | 186.1 | 184 | 121 | 114 | 38 | 73 | 160 | 4 | 0 | 0 | 0 | 14 | 3 | 3 | 5.16 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 73 | 33 | 33 | 6 | 12 | 5.93 | .352 | 1.57 | 10.5 | 3.7 | 8.4 | 145.2 | 169 | 105 | 96 | 27 | 59 | 135 | 0 | 0 | 0 | 0 | 6 | 9 | 3 | 4.97 |
| SP | Nelson, R.Nelson, Roger >> | 28 | 1972 | R | 87 | 31 | 31 | 12 | 5 | 4.30 | .300 | 1.28 | 8.2 | 3.3 | 6.2 | 159.0 | 144 | 80 | 76 | 18 | 59 | 109 | 0 | 0 | 0 | 0 | 7 | 1 | 6 | 4.23 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 70 | 0 | 3 | 10 | 3.10 | .251 | 0.99 | 6.9 | 2.1 | 13.1 | 72.2 | 55 | 25 | 25 | 13 | 17 | 105 | 0 | 39 | 4 | 0 | 0 | 1 | 2 | 3.18 |
| RP | Capps, C.Capps, Carter >> | 24 | 2015 | R | 83 | 92 | 0 | 10 | 2 | 2.95 | .297 | 1.27 | 8.4 | 3.1 | 11.1 | 91.2 | 85 | 30 | 30 | 8 | 31 | 112 | 0 | 3 | 3 | 0 | 0 | 0 | 3 | 2.70 |
| RP | Britton, Z.Britton, Zach >> | 28 | 2016 | L | 76 | 93 | 0 | 3 | 1 | 3.51 | .259 | 1.04 | 6.0 | 3.4 | 9.5 | 66.2 | 44 | 27 | 26 | 7 | 25 | 70 | 0 | 0 | 0 | 0 | 0 | 1 | 3 | 3.44 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 70 | 64 | 0 | 2 | 2 | 4.30 | .288 | 1.15 | 6.8 | 3.6 | 9.2 | 73.1 | 55 | 37 | 35 | 12 | 29 | 75 | 0 | 1 | 1 | 0 | 0 | 5 | 0 | 4.48 |
| SP | Hendricks, K.Hendricks, Kyle >> | 26 | 2016 | R | 73 | 11 | 0 | 1 | 3 | 7.94 | .404 | 2.03 | 15.5 | 3.3 | 5.7 | 11.1 | 19 | 10 | 10 | 5 | 4 | 7 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 8.73 |
| SP | Saberhagen, B.Saberhagen, Bret # >> | 25 | 1989 | R | 64 | 27 | 0 | 3 | 1 | 6.54 | .358 | 1.64 | 11.0 | 3.8 | 6.4 | 106.0 | 129 | 77 | 77 | 19 | 45 | 75 | 0 | 0 | 0 | 0 | 0 | 3 | 2 | 5.27 |