| SP | Kershaw, C.Kershaw, Clayton >> | 28 | 2016 | L | 98 | 20 | 20 | 10 | 8 | 3.49 | .289 | 1.21 | 9.5 | 1.5 | 9.1 | 136.2 | 143 | 56 | 53 | 20 | 23 | 138 | 2 | 0 | 0 | 0 | 13 | 1 | 3 | 3.41 |
| SP | McClanahan, S.McClanahan, Shane >> | 25 | 2022 | L | 89 | 20 | 20 | 6 | 5 | 4.15 | .316 | 1.36 | 8.7 | 3.6 | 9.6 | 108.1 | 104 | 53 | 50 | 16 | 43 | 115 | 0 | 0 | 0 | 0 | 8 | 3 | 3 | 4.07 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 19 | 19 | 6 | 6 | 5.58 | .336 | 1.50 | 9.3 | 4.2 | 10.4 | 100.0 | 103 | 63 | 62 | 26 | 47 | 115 | 0 | 0 | 0 | 0 | 6 | 2 | 2 | 5.55 |
| SP | Gooden, D.Gooden, Dwight >> | 21 | 1985 | R | 75 | 18 | 18 | 7 | 6 | 5.08 | .296 | 1.25 | 8.3 | 2.9 | 6.7 | 108.0 | 100 | 63 | 61 | 19 | 35 | 80 | 1 | 0 | 0 | 0 | 8 | 1 | 4 | 4.81 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 95 | 17 | 17 | 5 | 10 | 5.85 | .301 | 1.27 | 9.1 | 2.4 | 9.3 | 95.1 | 96 | 63 | 62 | 19 | 25 | 98 | 4 | 0 | 0 | 0 | 6 | 2 | 3 | 4.39 |
| CL | Kimbrel, C.Kimbrel, Craig † >> | 24 | 2012 | R | 100 | 41 | 0 | 3 | 2 | 2.61 | .257 | 1.04 | 5.3 | 4.2 | 10.8 | 41.1 | 24 | 12 | 12 | 3 | 19 | 49 | 0 | 28 | 3 | 0 | 0 | 0 | 0 | 2.95 |
| RP | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 41 | 0 | 4 | 5 | 3.51 | .225 | 0.87 | 5.5 | 2.4 | 10.6 | 56.1 | 34 | 24 | 22 | 6 | 15 | 66 | 0 | 2 | 1 | 0 | 0 | 0 | 0 | 2.84 |
| SU | Edwards, C.Edwards, Carl # >> | 24 | 2016 | R | 93 | 35 | 0 | 1 | 2 | 5.45 | .333 | 1.50 | 9.0 | 4.8 | 11.6 | 34.2 | 34 | 21 | 21 | 3 | 18 | 44 | 0 | 2 | 4 | 0 | 0 | 0 | 5 | 3.15 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 23 | 0 | 1 | 2 | 3.24 | .292 | 1.24 | 9.4 | 1.8 | 10.8 | 25.0 | 26 | 10 | 9 | 5 | 5 | 30 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.80 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 71 | 21 | 0 | 1 | 0 | 6.43 | .292 | 1.24 | 9.4 | 1.7 | 7.7 | 21.0 | 22 | 15 | 15 | 2 | 4 | 18 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.10 |
| SP | Perry, G.Perry, Gaylord >> | 34 | 1972 | R | 69 | 13 | 0 | 1 | 2 | 3.34 | .268 | 1.08 | 6.1 | 3.6 | 6.4 | 62.0 | 42 | 25 | 23 | 7 | 25 | 44 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 4.31 |