| SP | Severino, L.Severino, Luis >> | 28 | 2022 | R | 92 | 17 | 17 | 4 | 9 | 5.16 | .308 | 1.30 | 9.0 | 2.7 | 9.2 | 89.0 | 89 | 52 | 51 | 22 | 27 | 91 | 0 | 0 | 0 | 0 | 5 | 3 | 1 | 5.18 |
| SP | Urias, J.Urias, Julio # >> | 25 | 2022 | L | 89 | 17 | 17 | 6 | 6 | 3.96 | .286 | 1.17 | 8.4 | 2.2 | 9.2 | 102.1 | 95 | 45 | 45 | 14 | 25 | 104 | 0 | 0 | 0 | 0 | 8 | 3 | 0 | 3.57 |
| SP | Montgomery, J.Montgomery, Jordan >> | 29 | 2022 | L | 68 | 16 | 16 | 4 | 5 | 4.90 | .322 | 1.37 | 9.4 | 2.9 | 6.9 | 90.0 | 94 | 49 | 49 | 10 | 29 | 69 | 0 | 0 | 0 | 0 | 8 | 5 | 1 | 4.04 |
| SP | Urquidy, J.Urquidy, Jose >> | 27 | 2022 | R | 51 | 16 | 16 | 5 | 6 | 4.76 | .353 | 1.61 | 11.3 | 3.2 | 7.4 | 85.0 | 107 | 45 | 45 | 12 | 30 | 70 | 0 | 0 | 0 | 0 | 4 | 2 | 0 | 4.32 |
| SP | Gausman, K.Gausman, Kevin >> | 31 | 2022 | R | 38 | 16 | 16 | 4 | 6 | 5.72 | .343 | 1.49 | 11.0 | 2.4 | 10.4 | 85.0 | 104 | 58 | 54 | 10 | 23 | 98 | 0 | 0 | 0 | 0 | 6 | 6 | 4 | 3.25 |
| RP | Minter, A.Minter, A.J. >> | 28 | 2022 | L | 92 | 54 | 0 | 1 | 1 | 2.91 | .257 | 1.04 | 7.6 | 1.8 | 10.4 | 46.1 | 39 | 15 | 15 | 3 | 9 | 53 | 0 | 3 | 1 | 0 | 0 | 0 | 0 | 2.13 |
| RP | Boxberger, B.Boxberger, Brad >> | 34 | 2022 | R | 49 | 47 | 0 | 1 | 2 | 3.91 | .313 | 1.37 | 9.2 | 3.2 | 10.3 | 48.1 | 49 | 27 | 21 | 8 | 17 | 55 | 0 | 3 | 2 | 0 | 0 | 0 | 0 | 3.94 |
| RP | Lamet, D.Lamet, Dinelson >> | 29 | 2022 | R | 25 | 43 | 0 | 1 | 3 | 5.74 | .380 | 1.82 | 9.6 | 6.9 | 10.5 | 42.1 | 45 | 27 | 27 | 6 | 32 | 49 | 0 | 0 | 2 | 0 | 0 | 1 | 5 | 4.88 |