| SP | Gonsolin, T.Gonsolin, Tony >> | 28 | 2022 | R | 96 | 20 | 20 | 8 | 6 | 3.04 | .289 | 1.17 | 7.5 | 3.1 | 7.8 | 118.1 | 98 | 42 | 40 | 11 | 40 | 102 | 0 | 0 | 0 | 0 | 9 | 6 | 2 | 3.65 |
| SP | Ohtani, S.Ohtani, Shohei >> | 27 | 2022 | R | 90 | 20 | 20 | 6 | 7 | 4.00 | .313 | 1.30 | 8.9 | 2.9 | 9.2 | 123.2 | 121 | 57 | 55 | 8 | 40 | 126 | 0 | 0 | 0 | 0 | 11 | 8 | 5 | 2.97 |
| SP | Woodruff, B.Woodruff, Brandon # >> | 29 | 2022 | R | 83 | 19 | 19 | 4 | 7 | 4.91 | .328 | 1.43 | 10.2 | 2.6 | 10.1 | 110.0 | 125 | 62 | 60 | 15 | 32 | 123 | 0 | 0 | 0 | 0 | 8 | 4 | 0 | 3.52 |
| SP | Valdez, F.Valdez, Framber >> | 28 | 2022 | L | 71 | 19 | 19 | 9 | 7 | 3.90 | .351 | 1.57 | 9.9 | 4.3 | 7.1 | 115.1 | 126 | 57 | 50 | 8 | 55 | 91 | 0 | 0 | 0 | 0 | 12 | 6 | 9 | 3.91 |
| SP | Greene, H.Greene, Hunter >> | 22 | 2022 | R | 65 | 16 | 11 | 1 | 5 | 7.06 | .386 | 1.76 | 10.6 | 5.4 | 11.1 | 57.1 | 67 | 46 | 45 | 15 | 34 | 70 | 0 | 1 | 0 | 0 | 2 | 7 | 1 | 6.12 |
| SU | Swanson, E.Swanson, Erik >> | 28 | 2022 | R | 89 | 44 | 0 | 3 | 1 | 4.50 | .313 | 1.27 | 9.4 | 2.0 | 10.6 | 44.0 | 46 | 23 | 22 | 5 | 10 | 52 | 0 | 1 | 5 | 0 | 0 | 4 | 1 | 3.07 |
| RP | Jansen, K.Jansen, Kenley >> | 34 | 2022 | R | 77 | 51 | 0 | 2 | 5 | 4.80 | .299 | 1.26 | 8.4 | 3.0 | 10.2 | 65.2 | 61 | 35 | 35 | 6 | 22 | 74 | 0 | 0 | 2 | 0 | 0 | 1 | 1 | 2.98 |
| RP | Holmes, C.Holmes, Clay >> | 29 | 2022 | R | 72 | 48 | 0 | 4 | 2 | 3.72 | .321 | 1.37 | 8.3 | 4.1 | 9.8 | 55.2 | 51 | 24 | 23 | 10 | 25 | 60 | 0 | 2 | 2 | 0 | 0 | 3 | 1 | 4.71 |
| RP | Jimenez, J.Jimenez, Joe >> | 27 | 2022 | R | 62 | 41 | 0 | 4 | 0 | 3.45 | .316 | 1.32 | 8.8 | 3.1 | 11.5 | 47.0 | 46 | 18 | 18 | 5 | 16 | 60 | 0 | 1 | 1 | 0 | 0 | 3 | 0 | 3.04 |
| SP | Singer, B.Singer, Brady >> | 25 | 2022 | R | 63 | 17 | 8 | 1 | 2 | 7.18 | .356 | 1.58 | 11.3 | 3.0 | 8.9 | 77.2 | 97 | 63 | 62 | 9 | 26 | 76 | 0 | 0 | 0 | 0 | 2 | 6 | 0 | 3.79 |