| SP | Kershaw, C.Kershaw, Clayton † >> | 28 | 2016 | L | 99 | 21 | 21 | 10 | 6 | 3.03 | .243 | 0.94 | 6.9 | 1.6 | 8.3 | 151.1 | 115 | 52 | 51 | 7 | 27 | 140 | 9 | 0 | 0 | 3 | 14 | 4 | 1 | 2.36 |
| SP | Marichal, J.Marichal, Juan # >> | 29 | 1966 | R | 76 | 19 | 19 | 6 | 11 | 3.83 | .310 | 1.33 | 10.1 | 1.9 | 4.4 | 136.1 | 153 | 63 | 58 | 17 | 28 | 66 | 9 | 0 | 0 | 2 | 9 | 3 | 1 | 4.34 |
| SP | Krause, H.Krause, Harry >> | 21 | 1909 | L | 71 | 19 | 19 | 8 | 5 | 3.51 | .276 | 1.13 | 7.7 | 2.6 | 5.2 | 120.2 | 102 | 50 | 47 | 10 | 34 | 69 | 1 | 0 | 0 | 1 | 14 | 2 | 1 | 3.83 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 45 | 0 | 1 | 1 | 3.44 | .290 | 1.22 | 7.6 | 3.5 | 9.2 | 52.1 | 44 | 22 | 20 | 4 | 20 | 53 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 3.12 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 41 | 0 | 6 | 1 | 5.26 | .325 | 1.42 | 8.6 | 4.2 | 5.8 | 51.1 | 49 | 33 | 30 | 7 | 24 | 33 | 0 | 2 | 3 | 0 | 0 | 1 | 1 | 4.96 |
| RP | Zimmerman, J.Zimmerman, Jeff >> | 27 | 1999 | R | 70 | 30 | 0 | 1 | 1 | 4.50 | .311 | 1.35 | 8.7 | 3.4 | 4.5 | 34.0 | 33 | 20 | 17 | 2 | 13 | 17 | 0 | 4 | 1 | 0 | 0 | 0 | 1 | 3.91 |
| RP | Dotel, O.Dotel, Octavio >> | 29 | 2002 | R | 69 | 22 | 0 | 0 | 1 | 3.74 | .309 | 1.29 | 10.3 | 1.7 | 7.7 | 21.2 | 24 | 13 | 9 | 4 | 4 | 18 | 0 | 1 | 1 | 0 | 0 | 1 | 2 | 4.48 |
| RP | Valverde, J.Valverde, Jose >> | 24 | 2003 | R | 63 | 21 | 0 | 2 | 2 | 3.00 | .351 | 1.57 | 6.4 | 7.7 | 10.7 | 21.0 | 15 | 9 | 7 | 2 | 18 | 25 | 0 | 1 | 0 | 0 | 0 | 1 | 2 | 4.57 |
| SP | Caldwell, R.Caldwell, Ray >> | 26 | 1914 | R | 64 | 8 | 0 | 2 | 1 | 2.84 | .309 | 1.34 | 8.3 | 4.5 | 3.8 | 12.2 | 11 | 5 | 4 | 0 | 6 | 5 | 0 | 1 | 0 | 0 | 0 | 0 | 0 | 3.67 |