| SP | Koufax, S.Koufax, Sandy >> | 30 | 1965 | L | 98 | 21 | 21 | 6 | 11 | 4.60 | .322 | 1.41 | 8.9 | 3.8 | 8.4 | 164.1 | 162 | 86 | 84 | 13 | 69 | 153 | 6 | 0 | 0 | 0 | 9 | 3 | 10 | 3.48 |
| SP | Bender, C.Bender, Chief # >> | 26 | 1910 | R | 71 | 19 | 19 | 5 | 11 | 4.93 | .306 | 1.31 | 9.7 | 2.1 | 5.6 | 142.1 | 153 | 78 | 78 | 16 | 33 | 88 | 9 | 0 | 0 | 0 | 7 | 2 | 5 | 3.96 |
| SP | Schmidt, J.Schmidt, Jason >> | 30 | 2003 | R | 68 | 21 | 19 | 10 | 9 | 4.27 | .319 | 1.38 | 9.8 | 2.7 | 7.4 | 139.0 | 151 | 71 | 66 | 16 | 41 | 115 | 3 | 0 | 0 | 0 | 10 | 3 | 1 | 3.79 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 44 | 0 | 0 | 3 | 3.40 | .299 | 1.28 | 8.4 | 3.3 | 10.1 | 47.2 | 44 | 19 | 18 | 5 | 17 | 53 | 0 | 5 | 2 | 0 | 0 | 0 | 0 | 3.21 |
| RP | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 97 | 37 | 0 | 2 | 1 | 4.96 | .313 | 1.37 | 8.6 | 3.8 | 8.0 | 45.1 | 43 | 25 | 25 | 6 | 19 | 40 | 0 | 2 | 3 | 0 | 0 | 0 | 2 | 4.22 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 85 | 25 | 0 | 0 | 5 | 6.59 | .317 | 1.36 | 10.3 | 2.3 | 10.0 | 28.2 | 32 | 24 | 21 | 4 | 7 | 31 | 0 | 4 | 0 | 0 | 0 | 1 | 1 | 3.50 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 82 | 17 | 0 | 1 | 0 | 8.59 | .380 | 1.77 | 12.2 | 4.5 | 9.0 | 14.2 | 19 | 15 | 14 | 1 | 7 | 14 | 0 | 0 | 0 | 0 | 0 | 1 | 2 | 3.64 |
| RP | Clippard, T.Clippard, Tyler >> | 26 | 2011 | R | 79 | 14 | 0 | 2 | 0 | 7.02 | .324 | 1.44 | 7.3 | 6.2 | 7.3 | 16.2 | 13 | 13 | 13 | 3 | 11 | 13 | 0 | 1 | 2 | 0 | 0 | 0 | 0 | 5.88 |
| RP | Foulke, K.Foulke, Keith >> | 27 | 1999 | R | 59 | 14 | 0 | 0 | 0 | 7.24 | .369 | 1.76 | 13.2 | 3.5 | 7.6 | 13.2 | 19 | 11 | 11 | 2 | 5 | 11 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 4.46 |
| SP | Camnitz, H.Camnitz, Howie >> | 28 | 1909 | R | 56 | 2 | 0 | 1 | 0 | 2.45 | .267 | 0.95 | 6.4 | 2.6 | 5.1 | 7.1 | 5 | 2 | 2 | 0 | 2 | 4 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 3.14 |