| SP | Tiant, L.Tiant, Luis † >> | 28 | 1968 | R | 97 | 18 | 18 | 10 | 3 | 3.07 | .302 | 1.28 | 7.4 | 4.0 | 7.0 | 138.0 | 114 | 51 | 47 | 8 | 62 | 107 | 7 | 0 | 0 | 2 | 11 | 3 | 2 | 3.62 |
| SP | Kluber, C.Kluber, Corey # >> | 31 | 2017 | R | 89 | 18 | 18 | 6 | 6 | 3.79 | .304 | 1.25 | 9.0 | 2.3 | 9.5 | 126.0 | 126 | 61 | 53 | 19 | 32 | 133 | 2 | 0 | 0 | 0 | 12 | 7 | 0 | 3.78 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 41 | 0 | 5 | 4 | 3.26 | .287 | 1.17 | 7.3 | 3.3 | 8.4 | 58.0 | 47 | 28 | 21 | 8 | 21 | 54 | 0 | 2 | 5 | 0 | 0 | 2 | 0 | 4.12 |
| RP | Rivera, M.Rivera, Mariano >> | 39 | 2008 | R | 86 | 30 | 0 | 3 | 1 | 1.88 | .212 | 0.81 | 6.2 | 1.2 | 7.6 | 38.1 | 26 | 11 | 8 | 4 | 5 | 32 | 0 | 6 | 2 | 0 | 0 | 0 | 0 | 3.08 |
| RP | Wilhelm, H.Wilhelm, Hoyt >> | 43 | 1965 | R | 69 | 11 | 0 | 2 | 1 | 4.26 | .296 | 1.26 | 7.6 | 3.8 | 3.3 | 19.0 | 16 | 10 | 9 | 3 | 8 | 7 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 5.58 |
| RP | Drabowsky, M.Drabowsky, Moe >> | 31 | 1966 | R | 53 | 11 | 0 | 0 | 1 | 3.68 | .362 | 1.70 | 10.9 | 5.1 | 9.6 | 14.2 | 17 | 6 | 6 | 1 | 8 | 15 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.50 |