| SP | Verlander, J.Verlander, Justin >> | 36 | 2019 | R | 99 | 12 | 12 | 5 | 4 | 6.27 | .340 | 1.52 | 9.8 | 3.8 | 8.2 | 66.0 | 72 | 46 | 46 | 12 | 28 | 60 | 2 | 0 | 0 | 0 | 4 | 2 | 1 | 4.91 |
| SP | Kluber, C.Kluber, Corey >> | 31 | 2017 | R | 89 | 12 | 11 | 3 | 6 | 7.38 | .359 | 1.68 | 11.5 | 3.7 | 9.2 | 53.2 | 68 | 44 | 44 | 14 | 22 | 54 | 1 | 0 | 0 | 1 | 2 | 0 | 1 | 5.64 |
| SP | Hunter, C.Hunter, Catfish >> | 26 | 1972 | R | 81 | 11 | 11 | 3 | 4 | 6.67 | .357 | 1.67 | 11.3 | 3.7 | 5.7 | 54.0 | 68 | 40 | 40 | 10 | 22 | 34 | 0 | 0 | 0 | 0 | 3 | 0 | 0 | 5.37 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 76 | 10 | 10 | 0 | 5 | 8.26 | .417 | 2.13 | 12.5 | 7.0 | 6.5 | 44.2 | 61 | 41 | 41 | 9 | 34 | 32 | 0 | 0 | 0 | 0 | 1 | 1 | 1 | 6.59 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 92 | 34 | 0 | 4 | 1 | 4.31 | .312 | 1.31 | 7.8 | 4.2 | 8.5 | 39.2 | 34 | 22 | 19 | 4 | 18 | 37 | 0 | 0 | 1 | 0 | 0 | 2 | 0 | 3.97 |
| RP | Soriano, R.Soriano, Rafael >> | 24 | 2003 | R | 84 | 27 | 0 | 0 | 1 | 2.41 | .297 | 1.24 | 8.1 | 3.1 | 8.1 | 41.0 | 37 | 11 | 11 | 2 | 14 | 37 | 0 | 0 | 0 | 0 | 0 | 1 | 0 | 2.93 |
| RP | Hochevar, L.Hochevar, Luke >> | 30 | 2013 | R | 77 | 29 | 0 | 4 | 1 | 5.50 | .379 | 1.78 | 9.3 | 6.8 | 9.5 | 36.0 | 37 | 23 | 22 | 7 | 27 | 38 | 0 | 1 | 0 | 0 | 0 | 2 | 0 | 5.83 |