| SP | Buehler, W.Buehler, Walker >> | 23 | 2018 | R | 85 | 22 | 22 | 6 | 4 | 5.80 | .358 | 1.64 | 10.4 | 4.3 | 7.8 | 107.0 | 124 | 69 | 69 | 24 | 51 | 93 | 0 | 0 | 0 | 0 | 6 | 4 | 4 | 5.72 |
| SP | deGrom, J.deGrom, Jacob $ >> | 33 | 2021 | R | 100 | 22 | 22 | 7 | 8 | 4.89 | .319 | 1.39 | 9.4 | 3.1 | 10.8 | 123.1 | 129 | 72 | 67 | 16 | 43 | 147 | 0 | 0 | 0 | 0 | 12 | 1 | 0 | 3.37 |
| SP | Flaherty, J.Flaherty, Jack >> | 23 | 2019 | R | 82 | 21 | 21 | 7 | 5 | 4.88 | .329 | 1.45 | 9.1 | 4.0 | 9.3 | 110.2 | 111 | 60 | 60 | 13 | 49 | 114 | 0 | 0 | 0 | 0 | 8 | 3 | 4 | 3.88 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 75 | 44 | 0 | 3 | 3 | 2.56 | .251 | 0.97 | 5.2 | 3.6 | 9.0 | 52.2 | 30 | 15 | 15 | 4 | 21 | 52 | 0 | 4 | 1 | 0 | 0 | 2 | 0 | 3.33 |
| RP | Benoit, J.Benoit, Joaquin >> | 33 | 2010 | R | 94 | 55 | 0 | 7 | 2 | 4.19 | .299 | 1.27 | 8.9 | 2.6 | 9.4 | 68.2 | 67 | 37 | 32 | 9 | 20 | 71 | 0 | 7 | 6 | 0 | 0 | 1 | 0 | 3.56 |
| RP | Gregerson, L.Gregerson, Luke >> | 26 | 2010 | R | 72 | 30 | 0 | 3 | 1 | 5.46 | .300 | 1.29 | 8.7 | 2.9 | 10.3 | 28.0 | 27 | 18 | 17 | 7 | 9 | 32 | 0 | 4 | 1 | 0 | 0 | 0 | 0 | 4.93 |
| RP | Holland, G.Holland, Greg >> | 27 | 2013 | R | 70 | 26 | 0 | 0 | 0 | 4.62 | .339 | 1.54 | 9.4 | 4.7 | 11.9 | 25.1 | 26 | 13 | 13 | 9 | 13 | 33 | 0 | 3 | 0 | 0 | 0 | 0 | 1 | 6.60 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 67 | 16 | 0 | 0 | 3 | 8.56 | .328 | 1.46 | 9.0 | 4.8 | 10.4 | 13.2 | 13 | 14 | 13 | 3 | 7 | 15 | 0 | 1 | 0 | 0 | 0 | 0 | 3 | 5.31 |
| RP | Capps, C.Capps, Carter # >> | 24 | 2015 | R | 84 | 50 | 0 | 3 | 4 | 6.48 | .359 | 1.64 | 9.7 | 5.0 | 12.4 | 50.0 | 54 | 37 | 36 | 13 | 28 | 69 | 0 | 4 | 3 | 0 | 0 | 2 | 3 | 5.42 |
| CL | Hader, J.Hader, Josh † >> | 24 | 2018 | L | 92 | 43 | 0 | 5 | 2 | 2.47 | .308 | 1.30 | 7.8 | 4.0 | 10.2 | 58.1 | 50 | 18 | 16 | 7 | 26 | 66 | 0 | 14 | 2 | 0 | 0 | 2 | 0 | 3.74 |
| SP | Strider, S.Strider, Spencer >> | 24 | 2023 | R | 40 | 22 | 0 | 5 | 2 | 5.11 | .344 | 1.53 | 9.0 | 4.9 | 8.8 | 75.2 | 75 | 45 | 43 | 16 | 41 | 73 | 0 | 0 | 0 | 0 | 0 | 3 | 0 | 5.59 |