| SP | Scherzer, M.Scherzer, Max $$ >> | 33 | 2017 | R | 97 | 23 | 23 | 10 | 8 | 4.01 | .296 | 1.22 | 8.0 | 3.0 | 9.4 | 150.1 | 134 | 67 | 67 | 27 | 50 | 157 | 1 | 0 | 0 | 0 | 15 | 6 | 4 | 4.37 |
| SP | McClanahan, S.McClanahan, Shane $$ >> | 25 | 2022 | L | 89 | 22 | 22 | 5 | 10 | 5.49 | .328 | 1.42 | 9.4 | 3.4 | 9.1 | 132.2 | 138 | 85 | 81 | 26 | 50 | 134 | 0 | 0 | 0 | 0 | 8 | 6 | 7 | 4.80 |
| SP | Fernandez, J.Fernandez, Jose >> | 21 | 2013 | R | 83 | 22 | 22 | 6 | 6 | 3.58 | .293 | 1.24 | 6.9 | 4.4 | 9.2 | 140.2 | 107 | 60 | 56 | 14 | 68 | 143 | 0 | 0 | 0 | 0 | 14 | 0 | 4 | 3.71 |
| SP | Liriano, F.Liriano, Francisco >> | 23 | 2006 | L | 75 | 21 | 21 | 10 | 2 | 3.76 | .266 | 1.06 | 6.7 | 2.8 | 9.5 | 103.0 | 77 | 44 | 43 | 15 | 32 | 109 | 0 | 0 | 0 | 0 | 3 | 3 | 1 | 3.80 |
| SP | Hudson, D.Hudson, Daniel >> | 23 | 2010 | R | 72 | 21 | 20 | 11 | 6 | 5.64 | .358 | 1.66 | 10.6 | 4.3 | 7.2 | 121.1 | 143 | 80 | 76 | 23 | 58 | 97 | 0 | 0 | 0 | 0 | 8 | 2 | 5 | 5.36 |
| CL | Jansen, K.Jansen, Kenley >> | 28 | 2016 | R | 96 | 54 | 0 | 3 | 6 | 3.05 | .236 | 0.89 | 5.8 | 2.3 | 10.1 | 56.0 | 36 | 19 | 19 | 8 | 14 | 63 | 0 | 28 | 3 | 0 | 0 | 2 | 0 | 3.46 |
| SU | Papelbon, J.Papelbon, Jonathan >> | 27 | 2007 | R | 91 | 46 | 0 | 2 | 3 | 3.31 | .303 | 1.29 | 5.7 | 5.9 | 9.0 | 49.0 | 31 | 18 | 18 | 6 | 32 | 49 | 0 | 2 | 2 | 0 | 0 | 1 | 0 | 4.61 |
| RP | Percival, T.Percival, Troy >> | 26 | 1995 | R | 80 | 56 | 0 | 4 | 2 | 4.90 | .339 | 1.52 | 9.6 | 4.2 | 8.6 | 64.1 | 68 | 38 | 35 | 16 | 30 | 61 | 0 | 0 | 3 | 0 | 0 | 1 | 0 | 5.80 |
| RP | Gallegos, G.Gallegos, Giovanny >> | 27 | 2019 | R | 77 | 49 | 0 | 3 | 2 | 4.44 | .291 | 1.22 | 8.3 | 2.8 | 10.0 | 52.2 | 48 | 26 | 26 | 9 | 16 | 58 | 0 | 0 | 3 | 0 | 0 | 1 | 1 | 4.00 |
| SP | Millwood, K.Millwood, Kevin >> | 25 | 1999 | R | 70 | 20 | 0 | 6 | 0 | 3.86 | .338 | 1.47 | 9.0 | 4.3 | 6.3 | 72.1 | 72 | 34 | 31 | 6 | 34 | 50 | 0 | 1 | 0 | 0 | 0 | 5 | 0 | 4.32 |