| SP | Maddux, G.Maddux, Greg † $ >> | 29 | 1995 | R | 90 | 28 | 28 | 18 | 5 | 3.68 | .290 | 1.21 | 8.6 | 2.2 | 5.1 | 203.0 | 195 | 83 | 83 | 22 | 50 | 116 | 8 | 0 | 0 | 1 | 17 | 4 | 3 | 4.06 |
| SP | Harden, R.Harden, Rich $ >> | 27 | 2008 | R | 68 | 27 | 26 | 13 | 9 | 2.65 | .284 | 1.18 | 6.1 | 4.5 | 8.3 | 169.2 | 115 | 52 | 50 | 19 | 85 | 155 | 0 | 0 | 0 | 0 | 18 | 2 | 0 | 4.17 |
| SP | Nomo, H.Nomo, Hideo $$ >> | 27 | 1995 | R | 71 | 28 | 28 | 10 | 14 | 4.18 | .314 | 1.34 | 7.4 | 4.7 | 9.3 | 187.1 | 153 | 93 | 87 | 24 | 98 | 194 | 4 | 0 | 0 | 1 | 16 | 6 | 15 | 4.26 |
| RP | Feliz, N.Feliz, Neftali >> | 21 | 2009 | R | 97 | 72 | 0 | 2 | 1 | 2.49 | .244 | 0.95 | 5.0 | 3.6 | 8.2 | 79.2 | 44 | 23 | 22 | 4 | 32 | 72 | 0 | 3 | 3 | 0 | 0 | 1 | 0 | 3.09 |
| RP | Miller, A.Miller, Andrew >> | 29 | 2014 | L | 86 | 72 | 0 | 1 | 0 | 2.83 | .263 | 1.01 | 6.5 | 2.7 | 10.0 | 47.2 | 34 | 17 | 15 | 5 | 14 | 52 | 0 | 1 | 0 | 0 | 0 | 3 | 3 | 3.26 |
| RP | Rodney, F.Rodney, Fernando >> | 35 | 2012 | R | 80 | 50 | 0 | 3 | 2 | 3.14 | .259 | 1.01 | 7.1 | 2.1 | 8.1 | 57.1 | 45 | 20 | 20 | 5 | 13 | 51 | 0 | 1 | 0 | 0 | 0 | 2 | 2 | 3.14 |
| RP | Bautista, F.Bautista, Félix >> | 28 | 2023 | R | 72 | 30 | 0 | 3 | 5 | 3.07 | .279 | 1.13 | 6.5 | 3.7 | 11.8 | 29.1 | 21 | 10 | 10 | 0 | 12 | 38 | 0 | 1 | 1 | 0 | 0 | 1 | 4 | 1.72 |
| RP | Soria, J.Soria, Joakim >> | 24 | 2008 | R | 65 | 31 | 0 | 1 | 0 | 3.86 | .331 | 1.45 | 7.5 | 5.7 | 6.0 | 30.1 | 25 | 15 | 13 | 4 | 19 | 20 | 0 | 0 | 0 | 0 | 0 | 1 | 1 | 5.40 |
| SP | Messersmith, A.Messersmith, Andy >> | 30 | 1975 | R | 43 | 1 | 1 | 1 | 0 | 1.13 | .273 | 1.13 | 7.9 | 2.3 | 5.6 | 8.0 | 7 | 3 | 1 | 0 | 2 | 5 | 0 | 0 | 0 | 0 | 1 | 0 | 0 | 2.50 |
| CL | Chapman, A.Chapman, Aroldis >> | 37 | 2025 | L | 96 | 46 | 0 | 1 | 5 | 4.04 | .278 | 1.16 | 6.2 | 4.3 | 10.3 | 42.1 | 29 | 19 | 19 | 5 | 20 | 48 | 0 | 30 | 7 | 0 | 0 | 0 | 1 | 3.69 |