| SP | Pfiester, J.Pfiester, Jack >> | 28 | 1906 | L | 86 | 6 | 6 | 1 | 1 | 4.19 | .345 | 1.53 | 9.2 | 4.7 | 5.4 | 38.2 | 39 | 19 | 18 | 1 | 20 | 23 | 1 | 0 | 0 | 0 | 2 | 2 | 2 | 3.87 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 73 | 6 | 6 | 3 | 0 | 3.60 | .356 | 1.57 | 8.5 | 5.7 | 5.9 | 35.0 | 33 | 17 | 14 | 1 | 22 | 23 | 0 | 0 | 0 | 0 | 4 | 3 | 1 | 4.20 |
| SP | Arrieta, J.Arrieta, Jake >> | 29 | 2015 | R | 100 | 5 | 5 | 2 | 2 | 4.60 | .323 | 1.43 | 9.6 | 3.4 | 7.1 | 29.1 | 31 | 16 | 15 | 4 | 11 | 23 | 0 | 0 | 0 | 0 | 3 | 0 | 1 | 4.34 |
| SP | Harden, R.Harden, Rich >> | 27 | 2008 | R | 95 | 5 | 5 | 0 | 2 | 4.26 | .283 | 1.18 | 8.3 | 3.0 | 10.5 | 12.2 | 11 | 6 | 6 | 2 | 4 | 14 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 3.83 |
| SP | Keller, B.Keller, Brad >> | 29 | 2025 | R | 92 | 6 | 5 | 0 | 0 | 0.00 | .186 | 0.69 | 5.7 | 0.8 | 4.9 | 11.2 | 7 | 0 | 0 | 0 | 1 | 6 | 0 | 0 | 0 | 0 | 0 | 0 | 0 | 2.18 |
| RP | Tepera, R.Tepera, Ryan >> | 33 | 2021 | R | 92 | 17 | 0 | 1 | 0 | 1.67 | .214 | 0.81 | 4.7 | 2.7 | 7.3 | 27.0 | 14 | 5 | 5 | 2 | 8 | 22 | 0 | 0 | 1 | 0 | 0 | 0 | 0 | 3.22 |
| RP | Hodge, P.Hodge, Porter >> | 23 | 2024 | R | 83 | 15 | 0 | 4 | 1 | 2.50 | .308 | 1.33 | 6.5 | 5.5 | 8.5 | 18.0 | 13 | 5 | 5 | 2 | 11 | 17 | 0 | 0 | 1 | 0 | 0 | 0 | 3 | 4.39 |
| RP | Miller, T.Miller, Tyson >> | 28 | 2024 | R | 74 | 14 | 0 | 2 | 0 | 3.21 | .408 | 2.00 | 12.2 | 5.8 | 5.1 | 14.0 | 19 | 6 | 5 | 1 | 9 | 8 | 0 | 2 | 0 | 0 | 0 | 1 | 0 | 4.93 |
| RP | Edwards, C.Edwards, Carl >> | 24 | 2016 | R | 96 | 11 | 0 | 1 | 1 | 1.88 | .283 | 1.19 | 5.1 | 5.8 | 8.4 | 14.1 | 8 | 4 | 3 | 1 | 9 | 13 | 0 | 2 | 1 | 0 | 0 | 0 | 2 | 4.00 |
| RP | Kimbrel, C.Kimbrel, Craig >> | 33 | 2021 | R | 100 | 9 | 0 | 0 | 0 | 3.27 | .313 | 1.36 | 7.4 | 4.9 | 9.8 | 11.0 | 9 | 4 | 4 | 2 | 6 | 12 | 0 | 0 | 1 | 0 | 0 | 0 | 1 | 4.82 |