| SP | Leonard, D.Leonard, Dutch >> | 22 | 1914 | L | 91 | 31 | 31 | 9 | 11 | 3.76 | .294 | 1.23 | 7.4 | 3.7 | 4.5 | 191.1 | 157 | 90 | 80 | 19 | 78 | 96 | 1 | 0 | 0 | 1 | 18 | 4 | 4 | 4.58 |
| SP | Brown, M.Brown, Mordecai >> | 32 | 1908 | R | 85 | 30 | 30 | 13 | 11 | 4.08 | .297 | 1.24 | 8.7 | 2.5 | 3.5 | 211.2 | 205 | 103 | 96 | 20 | 58 | 81 | 6 | 0 | 0 | 1 | 16 | 5 | 4 | 4.36 |
| SP | Reulbach, E.Reulbach, Ed >> | 24 | 1906 | R | 61 | 30 | 30 | 15 | 6 | 3.60 | .324 | 1.43 | 8.5 | 4.5 | 3.7 | 202.2 | 190 | 85 | 81 | 15 | 100 | 82 | 3 | 0 | 0 | 0 | 20 | 2 | 1 | 4.67 |
| RP | Williams, D.Williams, Devin # >> | 28 | 2023 | R | 72 | 82 | 0 | 7 | 5 | 2.97 | .281 | 1.16 | 6.3 | 4.1 | 8.8 | 103.0 | 72 | 37 | 34 | 5 | 47 | 101 | 0 | 3 | 6 | 0 | 0 | 2 | 1 | 3.10 |
| RP | Balfour, G.Balfour, Grant >> | 31 | 2008 | R | 74 | 73 | 0 | 4 | 5 | 4.96 | .331 | 1.49 | 9.3 | 4.0 | 8.8 | 78.0 | 81 | 48 | 43 | 12 | 35 | 76 | 0 | 4 | 5 | 0 | 0 | 0 | 1 | 4.40 |
| RP | Bautista, F.Bautista, Félix # >> | 28 | 2023 | R | 75 | 61 | 0 | 5 | 4 | 5.02 | .317 | 1.34 | 6.9 | 5.2 | 9.3 | 61.0 | 47 | 39 | 34 | 7 | 35 | 63 | 0 | 0 | 1 | 0 | 0 | 3 | 8 | 4.30 |
| RP | Marmol, C.Marmol, Carlos >> | 26 | 2008 | R | 71 | 50 | 0 | 3 | 0 | 2.38 | .292 | 1.16 | 6.8 | 3.9 | 8.2 | 56.2 | 42 | 16 | 15 | 6 | 24 | 51 | 0 | 2 | 0 | 0 | 0 | 4 | 3 | 4.07 |
| CL | Benitez, A.Benitez, Armando >> | 32 | 2004 | R | 81 | 61 | 0 | 5 | 8 | 5.09 | .337 | 1.51 | 8.0 | 5.7 | 6.4 | 63.2 | 56 | 41 | 36 | 4 | 40 | 45 | 0 | 22 | 6 | 0 | 0 | 1 | 0 | 4.35 |